Italy Cruise Departures
Cruises that depart from Mediterranean: Italy
Cruises that visit Italy
See all River Cruises that depart from Italy
Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice
7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, La Goulette, Palermo, Civitavecchia, Savona
2026 Sails: Jan 3, Jan 10, Jan 17, More...
7 Night - Mediterranean
Starting in Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey, Corfu, Greece, Bari, Italy
2026 Sails: Jan 3, Jan 10, Jan 17, Jan 24, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, More...
24 Night - Star Collector : Winter Mediterranean Adventure
Starting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome, Livorno, Genoa, Italy, Nice, Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2026 Sails: Jan 4, Feb 12, More...8 Night - Winter Italy and the Dalmatian Coast
Starting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome
2026 Sails: Jan 4, Feb 12, Mar 23, More...15 Night - Star Collector : Winter in Europe's Rivieras & Croatia
Starting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome, Livorno, Genoa, Italy, Nice, Barcelona
2026 Sails: Jan 4, Feb 12, More...
78 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan
2026 Sails: Jan 5, More...32 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Colombia, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Jan 5, More...91 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Granada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva Islas, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore
2026 Sails: Jan 5, More...131 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Jan 5, More...
5 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain
2026 Sails: Jan 5, Apr 20, More...
Cruises that depart from Mediterranean: Italy
Cruises that visit Italy
See all River Cruises that depart from Italy
Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice
7 Night - Western Mediterranean from SavonaStarting in Savona, Marseille, Barcelona, La Goulette, Palermo, Civitavecchia, Savona
2026 Sails: Jan 3, Jan 10, Jan 17, More...
7 Night - MediterraneanStarting in Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey, Corfu, Greece, Bari, Italy
2026 Sails: Jan 3, Jan 10, Jan 17, Jan 24, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, More...
24 Night - Star Collector : Winter Mediterranean AdventureStarting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome, Livorno, Genoa, Italy, Nice, Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2026 Sails: Jan 4, Feb 12, More...
8 Night - Winter Italy and the Dalmatian CoastStarting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome
2026 Sails: Jan 4, Feb 12, Mar 23, More...
15 Night - Star Collector : Winter in Europe's Rivieras & CroatiaStarting in Venice, Zadar, Dubrovnik, Croatia, Messina (Taormina), Naples, Rome, Livorno, Genoa, Italy, Nice, Barcelona
2026 Sails: Jan 4, Feb 12, More...
78 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan
2026 Sails: Jan 5, More...
32 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Colombia, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Jan 5, More...
91 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Granada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva Islas, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore
2026 Sails: Jan 5, More...
131 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Jan 5, More...
5 Night - MediterraneanStarting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain
2026 Sails: Jan 5, Apr 20, More...
