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Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Departing from
Italy
Cruise Specials

MSC Cruises, MSC Grandiosa
MSC Grandiosa Cruises1 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Marseille (Provence), France
2025 Sails: Nov 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa Cruises2 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2025 Sails: Nov 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa Cruises16 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Las Palmas de Gran Canaria (Canary Islands), Spain, Philipsburg, St Maarten, San Juan, Puerto Rico, Miami, Florida
2025 Sails: Nov 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa Cruises17 Night - Msc Grand Voyages
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Las Palmas de Gran Canaria (Canary Islands), Spain, Philipsburg, St Maarten, San Juan, Puerto Rico, Miami, Florida, Port Canaveral (Orlando), Florida
2025 Sails: Nov 19, More...
MSC Cruises, MSC Orchestra
MSC Orchestra Cruise Ship7 Night - Mediterranean
Starting in Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy
2025 Sails: Nov 19, Dec 10, Dec 17, Dec 24, Dec 31, 2026: Jan 7, Jan 14, Jan 21, Jan 28, Feb 4, Feb 11, Feb 18, Feb 25, Mar 4, Mar 11, Mar 18, Mar 25, Apr 1, Apr 8, Apr 15, Dec 2, Dec 9, Dec 16, Dec 23, More...
MSC Cruises, MSC Splendida
MSC Splendida Cruise Ship7 Night - Mediterranean
Starting in Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy
2025 Sails: Nov 19, Dec 3, Dec 10, Dec 17, Dec 24, Dec 31, 2026: Feb 11, Feb 18, Feb 25, Mar 4, Mar 11, Mar 18, Mar 25, Apr 1, Apr 8, Apr 15, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises18 Night - Transatlantic from Savona
Starting in Savona, Marseille, Malaga, Funchal, Santa Cruz de Tenerife, St Maarten (Philipsburg), Fort-de-France, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo
2025 Sails: Nov 20, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises22 Night - Transatlantic from Savona
Starting in Savona, Marseille, Malaga, Funchal, Santa Cruz de Tenerife, St Maarten (Philipsburg), Fort-de-France, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre
2025 Sails: Nov 20, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises15 Night - Transatlantic from Savona
Starting in Savona, Marseille, Malaga, Funchal, Santa Cruz de Tenerife, St Maarten (Philipsburg), Fort-de-France, Pointe-a-Pitre
2025 Sails: Nov 20, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa Cruises13 Night - Transatlantic from Savona
Starting in Savona, Marseille, Malaga, Funchal, Santa Cruz de Tenerife, St Maarten (Philipsburg)
2025 Sails: Nov 20, More...

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Italy Cruise Departures