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Colombia Cruise Departures

Cruises that depart from South America: Colombia

Cruises that visit Colombia

See all River Cruises that depart from Colombia

Click on a cruise ship itinerary sailing from Colombia (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colombia), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Barranquilla : Cartagena CO : Medellin


Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Feb 15, Mar 22, Apr 5, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2026 Sails: Mar 1, More...
AmaWaterways Cruise Tours, AmaMelodia Cruise Tours
AmaMelodia Cruise Tours12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2026 Sails: Mar 6, Mar 20, Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Mar 8, More...
AmaWaterways Cruise Tours, AmaMelodia Cruise Tours
AmaMelodia Cruise Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2026 Sails: Mar 9, Mar 23, Apr 6, May 4, May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...
AmaWaterways, AmaMelodia
AmaMelodia Cruises7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Mar 11, Mar 25, Apr 8, May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2026 Sails: Mar 15, Apr 12, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama, Cartagena CO
2026 Sails: Mar 29, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2026 Sails: Apr 19, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, More...

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Colombia Cruise Departures