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Colombia Cruise Departures

Cruises that depart from South America: Colombia

Cruises that visit Colombia

See all River Cruises that depart from Colombia

Click on a cruise ship itinerary sailing from Colombia (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colombia), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Barranquilla : Cartagena CO : Medellin


AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Mar 23, Apr 6, May 4, May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Oct 19, Nov 2, Nov 16, Nov 30, Dec 14, More...
AmaWaterways, AmaMelodia
AmaMelodia7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Mar 25, Apr 8, May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama, Cartagena CO
2026 Sails: Mar 29, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2026 Sails: Apr 19, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, More...
AmaWaterways, AmaMagdalena
AmaMagdalena7 Night - Magic of Colombia
Starting in Barranquilla, San Felipe, Magangue, Mompox, Calamar, Manzini, Cartagena CO, Colombia
2026 Sails: Jun 13, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Sep 6, More...
AmaWaterways, AmaMelodia
AmaMelodia7 Night - Wonders of Colombia
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Oct 21, More...
Lindblad Expeditions, National Geographic Quest
National Geographic Quest7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Gatun Lake, Panama City, Panama / Disembark Ship
2026 Sails: Nov 7, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2026 Sails: Nov 8, 2027: Apr 18, More...

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Colombia Cruise Departures