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South America Cruises

Cruises that visit South America

Cruises by region

See all South America River Cruises

Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Guyana : Peru : South Georgia / South Sandwich Islands : Suriname : Uruguay



Santa Cruz II Cruises14 Night - East Galapagos, Machu Picchu & Peru : Lima to Quito
Starting in Lima with stops in Sacred Valley, Machu Picchu, Machu Picchu & Cuzco, Guayaquil, Baltra & Mosquera Islet, San Cristobal Island, Santa Fe Island & South Plaza Island, Santa Cruz Island, Espanola Island, Eden Islet & North Seymour Island
2021 Sails: May 20, Jun 3, Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, Oct 21, Nov 4, Nov 18, Dec 2, Dec 16, Dec 30, More...
La Pinta Cruises7 Night - Darwins Discoveries - The Galapagos Islands Roundtrip Cruise from Guayaquil, Ecuador
Starting in Guayaquil, Ecuador; with stops in Isla Baltra; Isla Seymor Norte; Isla Isabela / Isla Fernandina; Isla Radiba / Isla Santa Cruz; Isla Floreana
2021 Sails: May 27, Jun 24, Jul 8, Aug 5, Sep 30, More...
Aria Amazon Cruises14 Night - Peruvian Amazon & Machu Picchu Exploration (2021) : Aria Amazon
Starting in Lima with stops in Yanayacu-Pucate River, Samiria River, Nauta, Ucayali River, Pacaya River, Clavero Lake, Urubamba, Aguas Calientes, Cusco
2021 Sails: Jun 2, Jun 30, Sep 1, Sep 29, Nov 3, Dec 1, More...
Aria Amazon Cruises10 Night - Peruvian Rivers & Rainforest Discovery (2021) : Aria Amazon
Starting in Lima with stops in Yanayacu-Pucate River, Samiria River, Nauta, Ucayali River, Pacaya River, Clavero Lake
2021 Sails: Jun 2, Jun 30, Sep 1, Sep 29, Nov 3, Dec 1, More...
National Geographic Endeavour II Cruises9 Night - Galapagos Aboard National Geographic Endeavour II Roundtrip Cruise from Guayaquil, Ecuador
Starting in Guayaquil, Ecuador; with stops in Galápagos/EMBARK; Galápagos Islands: Bartolomé, Santiago, Santa Cruz, Isabela, Fernandina, Floreana, Española; Galápagos/DISEMBARK; Guayaquil, Ecuador
2021 Sails: Jun 4, Jun 11, Jun 18, Jun 25, Jul 2, Jul 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, Nov 12, Nov 19, Nov 26, Dec 3, More...
National Geographic Endeavour II Cruises15 Night - Galapagos Aboard National Geographic Endeavour II + Perus Land of the Inca from Guayaquil to Lima
Starting in Guayaquil, Ecuador; with stops in Galápagos/EMBARK; Exploring the Galápagos Islands: Bartolomé, Santiago, Santa Cruz, Isabela, Fernandina, Floreana, Española; Galápagos/DISEMBARK; Guayaquil; Lima, Peru; Cusco; Sacred Valley of the Inca; Machu Picchu; Cusco; Lima, Peru
2021 Sails: Jun 4, Jun 11, Jun 18, Jun 25, Jul 2, Jul 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 24, Oct 1, Oct 8, Oct 15, Oct 22, Oct 29, Nov 5, Nov 12, Nov 19, Dec 3, Dec 10, More...
Lindblad Delfin II Cruises9 Night - Upper Amazon Aboard the Delfin II Roundtrip Cruise from Lima
Starting in Lima, Peru; with stops in Iquitos; Nauta/EMBARK; Exploring the Pacaya-Samiria Reserve; Nauta/DISEMBARK; Iquitos; Lima, Peru
2021 Sails: Jun 5, Jun 12, Jun 19, Jul 3, Jul 10, Jul 24, Jul 31, Aug 7, Aug 14, Oct 30, Nov 6, Dec 25, 2022: Jan 15, Jan 22, Jan 29, Feb 19, Feb 26, Mar 26, Apr 2, Apr 9, May 21, Jul 2, Jul 9, Jul 16, More...
National Geographic Islander cruise ship6 Night - Wild Galápagos Escape Roundtrip Cruise from Guayaquil, Ecuador
Starting in Guayaquil, Ecuador; with stops in Baltra, Galápagos/EMBARK; Galápagos: North Seymour, Santa Cruz, Isabela, Fernandina, San Cristobal, Española, Floreana; Baltra, Galápagos/DISEMBARK; Guayaquil, Ecuador
2021 Sails: Jun 5, Jun 10, Jun 19, Jun 24, Jul 3, Jul 17, Jul 22, Jul 31, Aug 5, Aug 14, Aug 19, Aug 28, Sep 2, Sep 11, Sep 25, Sep 30, Oct 9, Oct 14, Oct 23, Oct 28, Nov 6, Nov 11, Nov 20, Nov 25, More...
Silver Origin Cruises7 Night - OR210605007 - San Cristobal to Baltra
Starting in San Cristobal with stops in Kicker Rock, Isla Bartolome, Buccaneer Cove, Punta Vicente Roca (Isabela), Punta Espinoza, Tagus Cove (Isabela), Elizabeth Bay (Isabela), Post Office Bay (Floreana), Champion Islet (Floreana), Punta Cormorant (Floreana), Santa Cruz Highlands, Fausto Llerena Breeding Center, Cerro Dragon (Santa Cruz), Isla Guy Fawkes, Bahia Borrero, Baltra
2021 Sails: Jun 5, More...
National Geographic Islander cruise ship9 Night - Wild Galápagos & Peru Escape Cruise from Lima to Guayaquil
Starting in Lima, Peru; with stops in Cusco; Sacred Valley; Machu Picchu; Sacred Valley; Cusco; Lima; Guayaquil; Baltra/EMBARK; Galápagos: Isla Santa Cruz, Santa Fe, Plaza Sur, Sullivan Bay, Sombrero Chino, Genovesa; Baltra/DISEMBARK; Guayaquil, Ecuador
2021 Sails: Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, Dec 10, Dec 24, 2022: Jan 7, Jan 21, Feb 4, Feb 18, Mar 4, Mar 18, Apr 1, Apr 15, Apr 29, More...


South America Cruises

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