South America Cruises
Cruises that visit South America
Cruises by region
See all South America River Cruises
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay
47 Night - Remote Islands of the Pacific & New Guinea
Starting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia, Raiatea, Society Islands, French Polynesia, Aitutaki, Cook Islands, Cross International Dateline, Apia, Upolu, Samoa, Vavau, Tonga, Nuku Island, Tonga, Vanua Balavu, Fiji, Yasawa-i-Rara, Yasawa Island, Fiji, Lautoka, Fiji, Nabukeru, Yasawa Island, Fiji, Ambrym, Vanuatu, Pentecost Island, Vanuatu, Luganville, Espiritu Santo, Vanuatu, Alotau, Papua New Guinea, Per, Indonesia, Darwin, Australia
More...57 Night - Remote Islands of the Pacific & Kimberley Expedition
Starting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia, Raiatea, Society Islands, French Polynesia, Aitutaki, Cook Islands, Cross International Dateline, Apia, Upolu, Samoa, Vavau, Tonga, Nuku Island, Tonga, Vanua Balavu, Fiji, Yasawa-i-Rara, Yasawa Island, Fiji, Lautoka, Fiji, Nabukeru, Yasawa Island, Fiji, Ambrym, Vanuatu, Pentecost Island, Vanuatu, Luganville, Espiritu Santo, Vanuatu, Alotau, Papua New Guinea, Per, Indonesia, Darwin, Australia, King George River, Western Australia, Australia, Vansittart Bay, Western Australia, Australia, Ashmore Reef, Australia, Hunter River, Western Australia, Australia, Swift Bay, Australia, Freshwater Cove, Western Australia, Australia, Montgomery Reef, Western Australia, Australia, Talbot Bay, Western Australia, Australia, Lacepede Islands, Western Australia, Australia, Broome, Western Australia, Australia
More...19 Night - Easter & Pitcairn Islands : Marooned, Moai & Mutineers
Starting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia
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12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
15 Night - Galapagos by Catamaran, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 16, Oct 23, More...9 Night - Galapagos by Catamaran : An Intimate Voyage
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 16, Oct 23, More...
9 Night - Exploring Galapagos
Starting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Sep 25, Oct 2, Oct 9, More...15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the Inca
Starting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Sep 25, Oct 2, Oct 9, More...
Cruises that visit South America
Cruises by region
See all South America River Cruises
Click on a cruise ship itinerary in South America (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just South America), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Argentina : Brazil : Chile : Colombia : Ecuador : Falkland Islands / Malvinas : French Guiana : Peru : South Georgia / South Sandwich Islands : Uruguay
47 Night - Remote Islands of the Pacific & New GuineaStarting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia, Raiatea, Society Islands, French Polynesia, Aitutaki, Cook Islands, Cross International Dateline, Apia, Upolu, Samoa, Vavau, Tonga, Nuku Island, Tonga, Vanua Balavu, Fiji, Yasawa-i-Rara, Yasawa Island, Fiji, Lautoka, Fiji, Nabukeru, Yasawa Island, Fiji, Ambrym, Vanuatu, Pentecost Island, Vanuatu, Luganville, Espiritu Santo, Vanuatu, Alotau, Papua New Guinea, Per, Indonesia, Darwin, Australia
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57 Night - Remote Islands of the Pacific & Kimberley ExpeditionStarting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia, Raiatea, Society Islands, French Polynesia, Aitutaki, Cook Islands, Cross International Dateline, Apia, Upolu, Samoa, Vavau, Tonga, Nuku Island, Tonga, Vanua Balavu, Fiji, Yasawa-i-Rara, Yasawa Island, Fiji, Lautoka, Fiji, Nabukeru, Yasawa Island, Fiji, Ambrym, Vanuatu, Pentecost Island, Vanuatu, Luganville, Espiritu Santo, Vanuatu, Alotau, Papua New Guinea, Per, Indonesia, Darwin, Australia, King George River, Western Australia, Australia, Vansittart Bay, Western Australia, Australia, Ashmore Reef, Australia, Hunter River, Western Australia, Australia, Swift Bay, Australia, Freshwater Cove, Western Australia, Australia, Montgomery Reef, Western Australia, Australia, Talbot Bay, Western Australia, Australia, Lacepede Islands, Western Australia, Australia, Broome, Western Australia, Australia
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19 Night - Easter & Pitcairn Islands : Marooned, Moai & MutineersStarting in San Antonio CL (Santiago), Chile, Juan Fernandez, Easter Island, Chile, Ducie Island, Pitcairn, Adamstown, Pitcairn Island, Pitcairn, Fakarava, Tuamotu, French Polynesia, Tahanea, French Polynesia, Anaa, French Polynesia, Papeete, French Polynesia
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12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
15 Night - Galapagos by Catamaran, Machu Picchu and Peru's Land of the IncaStarting in Quito or Guayaquil, Ecuador, Quito or Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 16, Oct 23, More...
9 Night - Galapagos by Catamaran : An Intimate VoyageStarting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 22, May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 16, Oct 23, More...
9 Night - Exploring GalapagosStarting in Quito or Guayaquil, Ecuador, Quito or Guayaquil, Galapagos Islands, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil or Quito, Guayaquil or Quito
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Sep 25, Oct 2, Oct 9, More...
15 Night - Exploring Galapagos, Machu Picchu and Peru's Land of the IncaStarting in Quito or Guayaquil, Ecuador, Guayaquil / Galapagos Islands / Embark Ship, Galapagos Islands, Galapagos Islands / Disembark Ship / Guayaquil / Lima, Peru, Lima, Lima / Cusco / Sacred Valley, Sacred Valley, Sacred Valley / Machu Picchu, Machu Picchu / Cusco, Cusco, Cusco / Lima
2026 Sails: Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Sep 25, Oct 2, Oct 9, More...
