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Colombia Cruise Departures

Cruises that depart from South America: Colombia

Cruises that visit Colombia

See all River Cruises that depart from Colombia

Click on a cruise ship itinerary sailing from Colombia (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colombia), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Barranquilla : Cartagena CO : Medellin


Crystal Cruises, Crystal Serenity
Crystal Serenity8 Night - The Americas & Caribbean
Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City)
2026 Sails: Dec 2, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity10 Night - The Americas & Caribbean
Starting in Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City), Puntarenas
2026 Sails: Dec 2, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Dec 20, 2027: Jan 31, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
AmaWaterways, AmaMelodia
AmaMelodia7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, 2028: Jan 5, Jan 19, Feb 2, Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 6, Mar 31, Apr 14, May 12, May 26, Jun 9, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, Dec 8, Dec 22, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2027 Sails: Jan 17, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Santa Marta, Colombia, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2027 Sails: Jan 24, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama, Cartagena CO
2027 Sails: Feb 14, More...

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Colombia Cruise Departures