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Cartagena CO Cruise Departures

Cruises that depart from South America: Colombia: Cartagena CO

Cruises that visit Cartagena CO

See all River Cruises that depart from Cartagena CO

Click on a cruise ship itinerary sailing from Cartagena CO (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Cartagena CO), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Royal Caribbean, Serenade of the Seas
Serenade of the Seas6 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2026 Sails: Apr 19, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: Apr 23, May 7, Jun 4, Jun 18, Jul 2, Jul 16, Aug 27, Sep 10, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, 2027: May 20, More...
AmaWaterways, AmaMagdalena
AmaMagdalena7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Apr 25, May 9, Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2027: May 22, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: Apr 25, May 9, Jun 6, Jun 20, Jul 4, Jul 18, Aug 29, Sep 12, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, 2027: May 22, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours9 Night - Wonders of Colombia with in Cartagena Pre Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla
2026 Sails: May 4, May 18, Jun 1, Jun 15, Aug 10, Aug 24, Sep 7, Nov 2, Nov 16, Nov 30, Dec 14, More...
AmaMelodia7 Night - Wonders of Colombia
Starting in Cartagena CO, Palenque, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, Dec 30, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, San Felipe, Barranquilla, Panama City
2026 Sails: May 6, May 20, Jun 3, Jun 17, Aug 12, Aug 26, Sep 9, Nov 4, Nov 18, Dec 2, Dec 16, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Sep 6, More...
Lindblad Expeditions, National Geographic Quest
National Geographic Quest7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Gatun Lake, Panama City, Panama / Disembark Ship
2026 Sails: Nov 7, More...

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Cartagena CO Cruise Departures