Medellin Cruise Departures
Cruises that depart from South America: Colombia: Medellin
Cruises that visit Medellin
See all River Cruises that depart from Medellin
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Nov 13, Nov 27, Dec 11, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Nov 13, Nov 27, Dec 11, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Nov 16, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Nov 16, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Nov 25, Dec 9, Dec 23, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Nov 25, Dec 9, Dec 23, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Dec 6, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Dec 6, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City
2027 Sails: Jan 8, Mar 5, Mar 19, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, 2028: Jan 7, Jan 21, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Sep 1, Sep 15, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla
2027 Sails: Jan 8, Mar 5, Mar 19, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, 2028: Jan 7, Jan 21, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Sep 1, Sep 15, More...
Cruises that depart from South America: Colombia: Medellin
Cruises that visit Medellin
See all River Cruises that depart from Medellin
Click on a cruise ship itinerary sailing from Medellin (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Medellin), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Nov 13, Nov 27, Dec 11, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Nov 13, Nov 27, Dec 11, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Nov 16, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Nov 16, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Nov 25, Dec 9, Dec 23, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Nov 25, Dec 9, Dec 23, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Dec 6, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Dec 6, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City
2027 Sails: Jan 8, Mar 5, Mar 19, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, 2028: Jan 7, Jan 21, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Sep 1, Sep 15, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla
2027 Sails: Jan 8, Mar 5, Mar 19, Apr 2, Apr 16, May 14, May 28, Jun 11, Aug 20, Sep 3, Oct 1, Oct 29, Nov 12, Nov 26, Dec 10, 2028: Jan 7, Jan 21, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Sep 1, Sep 15, More...
