Medellin Cruise Departures
Cruises that depart from South America: Colombia: Medellin
Cruises that visit Medellin
See all River Cruises that depart from Medellin
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Jan 17, Feb 14, Mar 14, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Jan 17, Feb 14, Mar 14, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
Cruises that depart from South America: Colombia: Medellin
Cruises that visit Medellin
See all River Cruises that depart from Medellin
Click on a cruise ship itinerary sailing from Medellin (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Medellin), please visit: Cruise Search or try our Virtual Cruise Advisor™.
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2027: May 17, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Jul 8, Aug 19, Sep 2, Sep 30, Oct 14, Oct 28, Nov 11, Nov 25, Dec 9, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Oct 25, Nov 8, Nov 22, Dec 6, More...
15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla, Panama City
2026 Sails: Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre CruiseStarting in Medellin, Cartagena CO, Colombia, Mahates, Calamar, Magangue, Mompox, Santa Barbara de Pinto, Sitionuevo, Barranquilla
2026 Sails: Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...
13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia, Panama City
2027 Sails: Jan 3, Jan 17, Feb 14, Mar 14, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
10 Night - Magic of Colombia with Medellin Pre CruiseStarting in Medellin, Barranquilla, Medellin, Sitionuevo, Santa Barbara de Pinto, Mompox, Magangue, Calamar, Cartagena CO, Colombia
2027 Sails: Jan 3, Jan 17, Feb 14, Mar 14, Mar 28, Apr 11, May 9, May 23, Jun 6, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, More...
