Medellin Cruise Departures

Cruises that depart from South America: Colombia: Medellin

Cruises that visit Medellin

See all River Cruises that depart from Medellin

Click on a cruise ship itinerary sailing from Medellin (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Medellin), please visit: Cruise Search or try our Virtual Cruise Advisor™.

AmaWaterways Cruise Tours, AmaMagdalena Cruise Tours

12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2026 Sails: Jan 12, Apr 6, Apr 20, May 4, Jun 1, Jun 15, Jun 29, Jul 13, Aug 24, Sep 7, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, Dec 14, 2027: May 17, More...

AmaWaterways Cruise Tours, AmaMelodia Cruise Tours

12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Manzini, Calamar, Magangue, Mompox, Barranquilla
2026 Sails: Jan 23, Mar 6, Mar 20, Apr 3, May 1, May 15, May 29, Jun 12, Aug 7, Aug 21, Sep 4, Oct 30, Nov 13, Nov 27, Dec 11, More...

AmaWaterways Cruise Tours, AmaMelodia Cruise Tours

12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Calamar, Mompox, Magangue, Barranquilla
2027 Sails: Jan 8, Jan 22, Mar 5, Mar 19, Apr 2, Apr 16, May 28, Jun 11, More...

AmaWaterways Cruise Tours, AmaMagdalena Cruise Tours

12 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise
Starting in Medellin, Cartagena CO, Colombia, Calamar, Mompox, Magangue, Barranquilla
2027 Sails: Jan 11, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, May 3, May 31, More...

Medellin Cruise Departures