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Colombia Cruise Departures

Cruises that depart from South America: Colombia

Cruises that visit Colombia

See all River Cruises that depart from Colombia

Click on a cruise ship itinerary sailing from Colombia (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colombia), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Barranquilla : Cartagena CO : Medellin


AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Oct 25, Nov 8, Nov 22, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Oct 25, Nov 8, Nov 22, More...
AmaWaterways, AmaMelodia
AmaMelodia7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Oct 28, Nov 11, Nov 25, Dec 23, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours10 Night - Magic of Colombia with Medellin Pre Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia
2026 Sails: Oct 28, Nov 11, Nov 25, Dec 9, Dec 23, More...
AmaWaterways Tours, AmaMelodia Tours
AmaMelodia Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Oct 28, Nov 11, Nov 25, More...
AmaWaterways, AmaMagdalena
AmaMagdalena7 Night - Magic of Colombia
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Palenque, Cartagena CO
2026 Sails: Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...
AmaWaterways Tours, AmaMagdalena Tours
AmaMagdalena Tours10 Night - Magic of Colombia with Panama Post Cruise
Starting in Barranquilla, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Nov 1, Dec 27, 2027: Jan 3, Jan 10, Feb 7, Feb 21, Feb 28, Mar 7, Mar 21, Apr 4, More...
Lindblad Expeditions, National Geographic Quest
National Geographic Quest7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Gatun Lake, Panama City, Panama / Disembark Ship
2026 Sails: Nov 7, More...

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Colombia Cruise Departures