Mississippi River Cruises
River Cruises sailing on the Mississippi River
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Apr 17, May 1, May 15, Nov 6, Nov 20, Dec 4, Dec 29, 2027: Jan 12, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 5, Nov 19, Dec 3, Dec 29, 2028: Jan 12, Mar 7, Apr 14, Apr 28, May 12, May 26, Oct 21, More...
8 Night - Music Cities Cruise
Starting in Memphis, TN, Day of River Cruising, Cruising the Ohio River, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Dover TN, Clarksville, TN, Nashville, TN
2026 Sails: Apr 21, Jul 14, Sep 8, 2027: Apr 20, Oct 8, More...8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, More...22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: May 22, 2027: Jun 4, 2028: Jun 2, More...
7 Night - Mississippi Delta Explorer
Starting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2026 Sails: May 23, Sep 26, Nov 24, Dec 8, 2027: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Oct 19, Nov 30, Dec 14, 2028: Feb 1, Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jun 2, Sep 25, Oct 18, 2028: May 30, More...8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Jun 9, Oct 25, 2028: Jun 6, More...
8 Night - Music Cities Cruise
Starting in Memphis, TN, Day of River Cruising, Cruising the Ohio River, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Dover TN, Clarksville, TN, Nashville, TN
2026 Sails: Jun 9, Jun 23, Jul 21, More...8 Night - Upper Mississippi River Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jun 12, Aug 21, Sep 4, Sep 18, Oct 2, 2027: Jun 25, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, 2028: Jun 23, Jul 8, Jul 21, Aug 4, Aug 19, Sep 1, Sep 15, More...
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 9, More...
River Cruises sailing on the Mississippi River
Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
8 Night - Lower Mississippi River CruiseStarting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Apr 17, May 1, May 15, Nov 6, Nov 20, Dec 4, Dec 29, 2027: Jan 12, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 5, Nov 19, Dec 3, Dec 29, 2028: Jan 12, Mar 7, Apr 14, Apr 28, May 12, May 26, Oct 21, More...
8 Night - Music Cities CruiseStarting in Memphis, TN, Day of River Cruising, Cruising the Ohio River, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Dover TN, Clarksville, TN, Nashville, TN
2026 Sails: Apr 21, Jul 14, Sep 8, 2027: Apr 20, Oct 8, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: May 22, 2027: Jun 4, 2028: Jun 2, More...
7 Night - Mississippi Delta ExplorerStarting in Memphis, Tennessee, Scenic Sailing Lower Mississippi, Greenville, Mississippi, Vicksburg, Mississippi, Natchez, Mississippi, St Francisville, Louisiana, Baton Rouge, Louisiana, Darrow, Louisiana, New Orleans, Louisiana
2026 Sails: May 23, Sep 26, Nov 24, Dec 8, 2027: Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Oct 19, Nov 30, Dec 14, 2028: Feb 1, Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jun 2, Sep 25, Oct 18, 2028: May 30, More...
8 Night - Lower Mississippi River CruiseStarting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Jun 9, Oct 25, 2028: Jun 6, More...
8 Night - Music Cities CruiseStarting in Memphis, TN, Day of River Cruising, Cruising the Ohio River, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Dover TN, Clarksville, TN, Nashville, TN
2026 Sails: Jun 9, Jun 23, Jul 21, More...
8 Night - Upper Mississippi River CruiseStarting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jun 12, Aug 21, Sep 4, Sep 18, Oct 2, 2027: Jun 25, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, 2028: Jun 23, Jul 8, Jul 21, Aug 4, Aug 19, Sep 1, Sep 15, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 9, More...
