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Ohio River Cruises

River Cruises sailing on the Ohio River

Click on a cruise ship itinerary sailing on the Ohio River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Ohio River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Ohio River also sail: Cumberland River : Lake Barkley : Licking River : Mississippi River : Olentangy River : Tennessee River


American Duchess Cruises8 Night - Special Edition Voyages - History & Culture - The Art of Discovery River Cruise from Memphis to Louisville
Starting in Memphis, TN; with stops in Columbus, KY; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY
2021 Sails: May 30, Sep 19, 2022: May 7, Oct 15, More...
American Countess Cruises8 Night - Tennessee And Cumberland Rivers - Best of the Tennessee Cruise from Memphis to Chattanooga
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Savannah, TN; Decatur, AL; Chattanooga, TN
2021 Sails: Jun 5, Oct 30, More...
American Countess Cruises8 Night - Special Edition Voyages - History & Culture - Civil War: A Historical Perspective River Cruise from Memphis to Chattanooga
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Savannah, TN; Decatur, AL; Chattanooga, TN
2021 Sails: Jun 5, Oct 30, More...
American Duchess Cruises8 Night - Ohio River Exploration Cruise from Louisville to Pittsburgh
Starting in Louisville, KY; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Pittsburgh, PA
2021 Sails: Jun 6, 2022: Oct 22, 2023: Jul 1, Jul 15, Oct 14, More...
American Countess Cruises8 Night - Tennessee And Cumberland Rivers - Best of the Tennessee Cruise from Chattanooga to Memphis
Starting in Chattanooga, TN; with stops in Decatur, AL; Florence, AL; Savannah, TN; Paducah, KY; New Madrid, MO; Memphis, TN
2021 Sails: Jun 12, Nov 6, More...
American Countess Cruises8 Night - Special Edition Voyages - History & Culture - Civil War: A Historical Perspective River Cruise from Chattanooga to Memphis
Starting in Chattanooga, TN; with stops in Decatur, AL; Florence, AL; Savannah, TN; Paducah, KY; New Madrid, MO; Memphis, TN
2021 Sails: Jun 12, Nov 6, More...
American Duchess Cruises8 Night - Ohio River Exploration Cruise from Pittsburgh to Louisville
Starting in Pittsburgh, PA; with stops in Wheeling, WV; Marietta, OH; Huntington, WV; Augusta, KY; Cincinnati, OH; Madison, IN; Louisville, KY
2021 Sails: Jun 13, 2022: Oct 29, 2023: Jul 8, Jul 22, Oct 21, More...
American Duchess Cruises8 Night - Special Edition Voyages - Rhythm of the Rivers - An American Music Festival Cruise from Louisville to Nashville (Clarksville)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Dover, KY; Clarksville, TN
2021 Sails: Jun 20, 2022: May 14, More...
American Duchess Cruises8 Night - Tennessee And Cumberland Rivers - Soul of the South Cruise from Louisville to Nashville (Clarksville)
Starting in Louisville, KY; with stops in Brandenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; Dover, KY; Clarksville, TN
2021 Sails: Jun 20, 2022: May 14, More...
American Queen Cruises8 Night - Special Edition Voyages - Culinary & Cocktails - Bourbon - An American Spirit Cruise from Memphis to Louisville
Starting in Memphis, TN; with stops in New Madrid, MO; Paducah, KY; Henderson, KY; Owensboro, KY; Brandenburg, KY; Louisville, KY
2021 Sails: Jun 20, More...


Ohio River Cruises

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