Mississippi River Cruises
River Cruises sailing on the Mississippi River
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Nov 6, Nov 20, Dec 4, Dec 29, 2027: Jan 12, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 5, Nov 19, Dec 3, Dec 29, 2028: Jan 12, Mar 7, Apr 14, Apr 28, May 12, May 26, Oct 21, Nov 3, Nov 17, Dec 1, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, Nov 9, Nov 16, 2028: Mar 25, More...
8 Night - Arkansas River Cruise
Starting in Memphis, TN, Day of Cruising, Cleveland, MS, Day of River Cruising, Little Rock, AR, Fort Smith / Van Buren, AR, Muskogee, OK, Tulsa, OK
2026 Sails: Nov 8, 2027: May 21, 2028: Apr 7, Nov 5, More...
8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Nov 10, 2027: Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Oct 12, Oct 26, Nov 9, 2028: Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...
7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
7 Night - Nashville, Memphis & the Cumberland
Starting in Memphis, Tennessee, Scenic Sailing Upper Mississippi, Cape Girardeau, Missouri, Paducah, Kentucky, Clarksville, Tennessee, Nashville, Tennessee
2026 Sails: Nov 10, More...8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, Dec 8, More...8 Night - Arkansas River Cruise
Starting in Tulsa, OK, Day of Cruising, Muskogee, OK, Fort Smith / Van Buren, AR, Little Rock, AR, Day of River Cruising, Cleveland, MS, Memphis, TN
2026 Sails: Nov 15, 2027: May 28, 2028: Apr 14, Nov 12, More...7 Night - Gulf Coast Cruise
Starting in Pensacola, FL, Day of Cruising, Mobile, Al, Biloxi, MS, Ocean Springs, MS, Gulfport / Ship Island, MS, New Orleans, La
2026 Sails: Nov 16, Dec 14, Dec 26, 2027: Feb 18, Mar 2, Mar 14, Mar 26, Apr 7, Dec 16, Dec 28, 2028: Feb 26, Mar 9, Mar 21, Apr 2, More...7 Night - Nashville, Memphis & the Cumberland
Starting in Nashville, Tennessee, Clarksville, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, Scenic Sailing Upper Mississippi, Memphis, Tennessee
2026 Sails: Nov 17, More...
River Cruises sailing on the Mississippi River
Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Cruises on the Mississippi River also sail:
Arkansas River : Cumberland River : Lake Barkley : Lake Erie : Licking River : Ohio River : Tennessee River : US South Coast
8 Night - Lower Mississippi River CruiseStarting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Nov 6, Nov 20, Dec 4, Dec 29, 2027: Jan 12, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 5, Nov 19, Dec 3, Dec 29, 2028: Jan 12, Mar 7, Apr 14, Apr 28, May 12, May 26, Oct 21, Nov 3, Nov 17, Dec 1, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, Nov 9, Nov 16, 2028: Mar 25, More...
8 Night - Arkansas River CruiseStarting in Memphis, TN, Day of Cruising, Cleveland, MS, Day of River Cruising, Little Rock, AR, Fort Smith / Van Buren, AR, Muskogee, OK, Tulsa, OK
2026 Sails: Nov 8, 2027: May 21, 2028: Apr 7, Nov 5, More...
8 Night - Lower Mississippi River CruiseStarting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Nov 10, 2027: Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, May 11, May 25, Jun 8, Jun 22, Jul 6, Oct 12, Oct 26, Nov 9, 2028: Feb 15, Feb 29, Mar 14, Mar 28, Apr 11, Apr 25, May 9, May 23, Jun 6, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
7 Night - Nashville, Memphis & the CumberlandStarting in Memphis, Tennessee, Scenic Sailing Upper Mississippi, Cape Girardeau, Missouri, Paducah, Kentucky, Clarksville, Tennessee, Nashville, Tennessee
2026 Sails: Nov 10, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, Dec 8, More...
8 Night - Arkansas River CruiseStarting in Tulsa, OK, Day of Cruising, Muskogee, OK, Fort Smith / Van Buren, AR, Little Rock, AR, Day of River Cruising, Cleveland, MS, Memphis, TN
2026 Sails: Nov 15, 2027: May 28, 2028: Apr 14, Nov 12, More...
7 Night - Gulf Coast CruiseStarting in Pensacola, FL, Day of Cruising, Mobile, Al, Biloxi, MS, Ocean Springs, MS, Gulfport / Ship Island, MS, New Orleans, La
2026 Sails: Nov 16, Dec 14, Dec 26, 2027: Feb 18, Mar 2, Mar 14, Mar 26, Apr 7, Dec 16, Dec 28, 2028: Feb 26, Mar 9, Mar 21, Apr 2, More...
7 Night - Nashville, Memphis & the CumberlandStarting in Nashville, Tennessee, Clarksville, Tennessee, Paducah, Kentucky, Cape Girardeau, Missouri, Scenic Sailing Upper Mississippi, Memphis, Tennessee
2026 Sails: Nov 17, More...
