Mississippi River Cruises

Cruises sailing on the Mississippi River

Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Cruises on the Mississippi River also sail: Amstel River : Avon River : Corrib River : Cumberland River : Danube River : Ireland Coast : Lake Barkley : Licking River : Liffey River : Loch Lomond : Lough Leane : Main River : Ness River : Ohio River : Olentangy River : Ouse River : Rhine River : River Clyde : River Shannon : Salzach River : Suir River : Tennessee River : Water of Leith River

American Cruise Lines, America

7 Night Mississippi River from Memphis, TN to New Orleans, LA
Starting in Memphis, Tennessee; with stops in Vicksburg, Mississippi; Natchez, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Oak Alley, Louisiana; New Orleans, Louisiana
2019 Sails: Jun 1, Jun 15, Jun 29, Nov 2, Nov 16, Nov 30, Dec 28, 2020: Mar 28, Apr 11, Apr 25, May 16, May 30, Jun 13, More...

American Cruise Lines, Queen of the Mississippi

7 Night Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2019 Sails: Jun 1, Nov 2, 2020: Mar 28, Apr 11, May 2, May 16, May 30, More...

American Cruise Lines, American Harmony

7 Night New Orleans to New Orleans Cruise New Orleans, Louisiana to New Orleans, Louisiana
Starting in New Orleans, with stops in Oak Alley, Natchez, Vicksburg, St Francisville, Baton Rouge, Houmas House, New Orleans
2019 Sails: Jun 2, Sep 28, Nov 8, Nov 15, Nov 22, Dec 5, Dec 12, Dec 20, Dec 28, 2020: Nov 5, Dec 2, Dec 12, Dec 20, Dec 28, More...

American Queen Steamboat Company, American Duchess

8 Night Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2019 Sails: Jun 2, Jun 16, Jun 19, Jun 30, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, More...

American Queen Steamboat Company, American Queen

8 Night Lower Mississippi River Antebellum South Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Jun 2, Jun 16, Sep 1, Sep 15, Sep 29, Oct 13, Nov 10, Nov 24, More...

American Cruise Lines, America

7 Night Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2019 Sails: Jun 8, Jun 22, Jul 8, Oct 26, Nov 9, Nov 23, Dec 20, 2020: Mar 21, Apr 4, Apr 18, May 9, May 23, Jun 6, More...

American Cruise Lines, Queen of the Mississippi

7 Night Mississippi River from Memphis, TN to New Orleans, LA
Starting in Memphis, Tennessee; with stops in Vicksburg, Mississippi; Natchez, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Oak Alley, Louisiana; New Orleans, Louisiana
2019 Sails: Jun 8, Nov 9, 2020: Apr 4, Apr 18, May 9, May 23, More...

American Cruise Lines, American Harmony

7 Night Lower Mississippi River Cruise New Orleans, Louisiana to Memphis, Tennessee
Starting in New Orleans, with stops in Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Cruising the Mississippi River, Memphis
2019 Sails: Jun 9, Jun 23, Jul 7, Jul 21, Oct 5, 2020: Feb 23, Mar 8, Mar 22, Apr 5, Apr 19, May 10, May 24, Jun 7, Oct 8, Oct 22, More...

American Queen Steamboat Company, American Duchess

8 Night Lower Mississippi River Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Helena, AR; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Jun 9, Jun 23, Sep 22, Oct 6, Oct 20, Nov 3, Nov 17, More...

American Queen Steamboat Company, American Queen

8 Night Lower Mississippi River Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Jun 9, Aug 25, Sep 8, Sep 22, Oct 6, Oct 20, Nov 17, Dec 1, More...

More =>

Mississippi River Cruises