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Mississippi River Cruises

Cruises sailing on the Mississippi River


Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Cruises on the Mississippi River also sail: Amstel River : Avon River : Corrib River : Cumberland River : Danube River : Ireland Coast : Lake Barkley : Licking River : Liffey River : Loch Lomond : Lough Leane : Main River : Ness River : Ohio River : Ouse River : Rhine River : Salzach River : Tennessee River : Water of Leith River




American Harmony Cruises7 Night New Orleans to New Orleans Cruise New Orleans, Louisiana to New Orleans, Louisiana
Starting in New Orleans, with stops in Oak Alley, Natchez, Vicksburg, St Francisville, Baton Rouge, Houmas House, New Orleans
2019 Sails: Nov 15, Nov 22, Dec 5, Dec 12, Dec 20, Dec 28, 2021: Feb 14, Oct 3, More...
America Cruises7 Night Mississippi River from Memphis, TN to New Orleans, LA
Starting in Memphis, Tennessee; with stops in Vicksburg, Mississippi; Natchez, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Oak Alley, Louisiana; New Orleans, Louisiana
2019 Sails: Nov 16, Nov 30, Dec 28, 2020: Mar 28, Apr 11, Apr 25, May 16, May 30, Jun 13, Jun 27, 2021: Jun 20, More...
Queen of the Mississippi Cruises7 Night Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2019 Sails: Nov 16, 2020: Mar 28, Apr 11, May 2, May 16, May 30, Oct 31, Nov 14, 2021: Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Nov 13, Nov 27, More...
American Duchess Cruises8 Night Lower Mississippi River Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Helena, AR; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Nov 17, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Nov 17, Dec 1, More...
America Cruises7 Night Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2019 Sails: Nov 23, Dec 20, 2020: Mar 21, Apr 4, Apr 18, May 9, May 23, Jun 6, More...
Queen of the Mississippi Cruises7 Night Mississippi River from Memphis, TN to New Orleans, LA
Starting in Memphis, Tennessee; with stops in Vicksburg, Mississippi; Natchez, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Oak Alley, Louisiana; New Orleans, Louisiana
2019 Sails: Nov 23, 2020: Apr 4, Apr 18, May 9, May 23, Jun 6, Nov 7, Nov 21, 2021: Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Nov 20, Dec 4, More...
American Duchess Cruises8 Night Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2019 Sails: Nov 24, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Nov 24, More...
American Duchess Cruises8 Night Ohio and Tennessee River American Music Holiday from Memphis to Nashville
Starting in Memphis; with stops in Paducah, KY; Grand Rivers, KY; Clarksville, TN; Nashville, TN
2019 Sails: Dec 1, More...


Mississippi River Cruises
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