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Mississippi River Cruises

Cruises sailing on the Mississippi River


Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Cruises on the Mississippi River also sail: Amstel River : Avon River : Corrib River : Cumberland River : Danube River : Ireland Coast : Lake Barkley : Licking River : Liffey River : Loch Lomond : Lough Leane : Main River : Ness River : Ohio River : Olentangy River : Ouse River : Rhine River : Salzach River : Suir River : Tennessee River : Water of Leith River




Scenic Opal Cruises2019 - 35 Night Jewels of Europe with Majestic Britain & Ireland: London to Budapest aboard Scenic Opal (Combo)
Starting in London with stops in Bath, Waterford, Killarney, Ring of Kerry, Galway, Dublin, Chester, Lake District, Loch Lomond, Inverness, Edinburgh, York, Stratford, Amsterdam, Marksburg, Rudesheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Salzburg, Durnstein, Vienna, Budapest
2019 Sails: Sep 18, More...
Queen of the Mississippi Cruises7 Night Cumberland River Cruise from St. Louis to Nashville
Starting in St. Louis, MO; with stops in Chester, IL; Cape Girardeau, MO; Paducah, KY; Dover, TN; Clarksville, TN; Nashville, TN
2019 Sails: Sep 21, 2020: Sep 5, Sep 19, More...
American Duchess Cruises8 Night Lower Mississippi River Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Helena, AR; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Sep 22, Oct 6, Oct 20, Nov 3, Nov 17, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Sep 22, Oct 6, Oct 20, Nov 17, Dec 1, More...
America Cruises7 Night Upper Mississippi River from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Davenport, IA; Hannibal, MO; St. Louis, MO
2019 Sails: Sep 24, 2020: Sep 27, More...
American Harmony Cruises7 Night New Orleans to New Orleans Cruise New Orleans, Louisiana to New Orleans, Louisiana
Starting in New Orleans, with stops in Oak Alley, Natchez, Vicksburg, St Francisville, Baton Rouge, Houmas House, New Orleans
2019 Sails: Sep 28, Nov 8, Nov 15, Nov 22, Dec 5, Dec 12, Dec 20, Dec 28, 2020: Nov 5, Dec 2, Dec 12, Dec 20, Dec 28, More...
Queen of the Mississippi Cruises7 Night Cumberland River and Mississippi River from Nashville, Tennessee to St. Louis, Missouri
Starting in Nashville, TN; with stops in Clarksville, TN; Dover; TN; Paducah, Kentucky; Cape Girardeau, MO; Chester, IL; St. Louis, Missouri
2019 Sails: Sep 28, 2020: Sep 12, Sep 26, More...
American Duchess Cruises8 Night Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2019 Sails: Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Sep 29, Oct 13, Nov 10, Nov 24, More...
America Cruises7 Night Mississippi River from St. Louis, MO to St. Paul, MN
Starting in St. Louis, MO; with stops in Hannibal, MO; Davenport, IA; Dubuque, IA; La Crosse, WI; Red Wing, MN; St. Paul, MN
2019 Sails: Oct 1, 2020: Sep 20, Oct 4, More...


Mississippi River Cruises
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