CruiseCompete: Easily Compare Multiple Offers from Cruise Experts
Compare offers from multiple travel agencies
1
Find your cruise
& request quotes
2
Compare members only prices,
upgrades, cabin credits & more!
3
Contact your preferred agent
for questions or to book your cruise
Over 1 million members
Mississippi River Cruises

Cruises sailing on the Mississippi River


Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Cruises on the Mississippi River also sail: Amstel River : Avon River : Corrib River : Cumberland River : Danube River : Ireland Coast : Lake Barkley : Licking River : Liffey River : Loch Lomond : Lough Leane : Main River : Ness River : Ohio River : Olentangy River : Ouse River : Rhine River : River Clyde : River Shannon : Salzach River : Suir River : Tennessee River : Water of Leith River


American Harmony Cruises7 Night Lower Mississippi River Cruise New Orleans, Louisiana to Memphis, Tennessee
Starting in New Orleans, with stops in Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Cruising the Mississippi River, Memphis
2019 Sails: Jul 21, Oct 5, 2020: Feb 23, Mar 8, Mar 22, Apr 5, Apr 19, May 10, May 24, Jun 7, Oct 8, Oct 22, More...
American Harmony Cruises10 Night Mississippi River Gateway Cruise New Orleans, Louisiana to St Louis, Missouri
Starting in New Orleans, with stops in Baton Rouge, Natchez, Vicksburg, Cruising the Mississippi River, Memphis, New Madrid, Paducah, Cruising the Ohio River, St Louis
2019 Sails: Jul 21, Oct 19, 2020: Jun 21, Jul 11, Sep 18, Nov 12, More...
American Duchess Cruises8 Night Ohio and Tennessee River Lewis and Clark Cruise from Pittsburgh to Louisville
Starting in Pittsburgh; with stops in Wheeling, WV; Marietta, OH; Huntington, WV; Augusta, KY; Cincinnati, OH; Madison, IN; Louisville, KY
2019 Sails: Jul 21, More...
American Queen Cruises8 Night Upper Mississippi Mark Twain's Mississippi from Alton to Red Wing
Starting in Alton, MO; with stops in Hannibal, MO; Clinton, IA; Dubuque, IA; La Crosse, WI; Red Wing MN
2019 Sails: Jul 21, Aug 4, More...
America Cruises10 Night Mississippi River Gateway Cruise from St. Louis to New Orleans
Starting in St. Louis, MO; with stops in Paducah, KY; New Madrid, MO; Memphis, TN; Vicksburg, MS, Natchez, MS; Baton Rouge, LA; New Orleans, LA
2019 Sails: Jul 24, More...
Scenic Crystal Cruises2019 - 35 Night Jewels of Europe with Majestic Britain & Ireland: London to Budapest aboard Scenic Crystal (Combo)
Starting in London with stops in Bath, Waterford, Killarney, Ring of Kerry, Athlone, Dublin, Chester, Lake District, Glasgow, Inverness, Edinburgh, York, Stratford, Amsterdam, Marksburg, Rudesheim, Wurzburg, Bamberg, Nuremberg, Regensburg, Salzburg, Durnstein, Vienna, Budapest
2019 Sails: Jul 24, More...
Queen of the Mississippi Cruises10 Night Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2019 Sails: Jul 25, 2020: Jul 3, Jul 23, More...
American Duchess Cruises8 Night Ohio and Tennessee River Lewis and Clark Cruise from Louisville to St. Louis
Starting in Louisville; with stops in Brandenburg, KY; Owensboro, KY; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO
2019 Sails: Jul 28, More...
American Queen Cruises8 Night Upper Mississippi Mark Twain's Mississippi from Red Wing to Alton
Starting in Minneapolis, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Bettendorf, IA; Burlington, IA; Hannibal, MO; Alton, IL
2019 Sails: Jul 28, More...
American Harmony Cruises7 Night Upper Mississippi River Cruise St Louis, Missouri to St Paul, Minnesota
Starting in St Louis, with stops in Hannibal, River Cruising, Davenport Iowa, Dubuque, La Crosse, Red Wing, St Paul
2019 Sails: Jul 31, 2020: Aug 28, More...


Mississippi River Cruises
Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Cruise news from Cruise Compete, where you compare cruise prices to get the best cruise discounts and deals
Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.