CruiseCompete: Easily Compare Multiple Offers from Cruise Experts
Compare offers from multiple travel agencies
1
Find your cruise
& request quotes
2
Compare members only prices,
upgrades, cabin credits & more!
3
Contact your preferred agent
for questions or to book your cruise
Over 1 million members
Mississippi River Cruises

Cruises sailing on the Mississippi River


Click on a cruise ship itinerary sailing on the Mississippi River (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Mississippi River), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Cruises on the Mississippi River also sail: Amstel River : Corrib River : Cumberland River : Danube River : Ireland Coast : Lake Barkley : Licking River : Liffey River : Loch Lomond : Lough Leane : Main River : Ness River : Ohio River : Ouse River : Rhine River : Salzach River : Tennessee River : Water of Leith River




American Duchess Cruises8 Night - Antebellum South Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2020 Sails: Jan 26, Feb 9, Mar 22, May 17, May 31, Jun 14, Oct 25, Nov 8, Nov 22, More...
American Duchess Cruises8 Night - A Taste of the True South Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Memphis, TN
2020 Sails: Feb 2, Mar 15, Mar 29, May 24, Jun 7, Aug 16, Nov 1, Nov 15, Nov 29, More...
America Cruises7 Night - Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2020 Sails: Feb 15, Feb 22, Feb 29, Mar 7, Mar 14, Jul 4, Jul 11, Jul 18, Dec 12, Dec 20, Dec 28, 2021: Feb 28, Mar 7, Mar 14, Apr 6, Apr 13, Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, Jun 8, More...
American Harmony Cruises7 Night - Lower Mississippi River Cruise from Memphis, Tennessee New Orleans, Louisiana
Starting in Memphis, with stops in Cruising the Mississippi River, Vicksburg, Natchez, St Francisville, Baton Rouge, Oak Alley, New Orleans
2020 Sails: Feb 16, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, May 17, May 31, Jun 14, Oct 15, Oct 29, More...
American Queen Cruises8 Night - Southern Sampler Cruise roundtrip from New Orleans
Starting in New Orleans; with stops in St. Francisville; Natchez; Vicksburg; Baton Rouge; Nottoway Plantation; New Orleans
2020 Sails: Feb 16, More...
American Harmony Cruises7 Night - Lower Mississippi River Cruise New Orleans, Louisiana to Memphis, Tennessee
Starting in New Orleans, with stops in Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Cruising the Mississippi River, Memphis
2020 Sails: Feb 23, Mar 8, Mar 22, Apr 5, Apr 19, May 10, May 24, Jun 7, Oct 8, Oct 22, More...
American Queen Cruises8 Night - Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2020 Sails: Feb 23, Mar 8, Mar 22, Apr 5, Apr 19, May 3, May 17, May 31, Jun 14, Jun 28, Jul 12, Aug 30, Sep 13, Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, More...
American Queen Cruises8 Night - Antebellum South Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2020 Sails: Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, May 10, May 24, Jun 7, Jun 21, Jul 5, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 29, Dec 13, More...
American Duchess Cruises8 Night - Southern Sampler Cruise roundtrip from New Orleans
Starting in New Orleans; with stops in St. Francisville; Natchez; Vicksburg; Baton Rouge; Nottoway Plantation; New Orleans
2020 Sails: Mar 8, More...
Queen of the Mississippi Cruises4 Night - Highlights of the Mississippi River roundtrip from New Orleans, LA
Starting in New Orleans, LA; with stops in Houmas House, LA; Baton Rouge, LA; Oak Alley, LA; New Orleans, LA
2020 Sails: Mar 12, Mar 16, Mar 20, Mar 24, More...


Mississippi River Cruises
Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Cruise news from Cruise Compete, where you compare cruise prices to get the best cruise discounts and deals
Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.