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Pittsburgh River Cruises

River Cruises that visit North America: United States: Pennsylvania: Pittsburgh

River Cruises that depart from Pittsburgh

See all Cruises that visit Pittsburgh

Ohio River Cruises

Click on a cruise ship itinerary that visits Pittsburgh (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Pittsburgh), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


American Cruise Lines, American Melody
American Melody Cruises15 Night - Grand Ohio River Cruise
Starting in St Louis, MO, Cruising the Mississippi River, Paducah, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Louisville, KY, Madison, IN, Cincinnati, OH, Day of Cruising, Maysville, KY, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jun 19, 2027: Jun 18, 2028: Jul 1, More...
American Cruise Lines, American Heritage
American Heritage Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, 2027: Jul 9, Jul 23, Aug 6, Aug 20, 2028: Jul 8, Jul 22, Aug 5, Aug 19, More...
American Cruise Lines, American Melody
American Melody Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 10, Jul 24, 2027: Jul 9, Jul 23, Aug 6, 2028: Jul 22, Aug 5, More...
American Cruise Lines, American Melody
American Melody Cruises15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Jul 31, 2027: Aug 13, 2028: Aug 12, More...
American Cruise Lines, American Heritage
American Heritage Cruises15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2026 Sails: Aug 21, 2027: Aug 27, 2028: Aug 26, More...
American Cruise Lines, American Symphony
American Symphony Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2027 Sails: Jul 16, 2028: Jul 15, More...
American Cruise Lines, American Symphony
American Symphony Cruises15 Night - Grand Ohio River Cruise
Starting in Pittsburgh, PA, Day of Cruising, Marietta, OH, Day of Cruising, Maysville, KY, Cincinnati, OH, Madison, IN, Louisville, KY, Day of Cruising, Henderson, KY / Evansville, IN, Day of Cruising, Paducah, KY, Day of Cruising, St Louis, MO
2027 Sails: Jul 23, 2028: Jul 22, More...

Pittsburgh River Cruises