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New Orleans River Cruise Departures

River Cruises that depart from North America: United States: Louisiana: New Orleans

River Cruises that visit New Orleans

See all Cruises that depart from New Orleans

Mississippi River Cruises

Click on a river cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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American Harmony Cruises10 Night - Mississippi River Gateway Cruise New Orleans, Louisiana to St Louis, Missouri
Starting in New Orleans, with stops in Baton Rouge, Natchez, Vicksburg, Cruising the Mississippi River, Memphis, New Madrid, Paducah, Cruising the Ohio River, St Louis
2020 Sails: Sep 18, Nov 12, More...
American Queen Cruises8 Night - Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2020 Sails: Sep 27, Oct 11, Oct 25, Nov 8, Nov 22, Dec 6, More...
American Countess Cruises7 Night - Antebellum South from New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2020 Sails: Oct 4, Oct 18, Nov 15, More...
American Harmony Cruises7 Night - Lower Mississippi River Cruise New Orleans, Louisiana to Memphis, Tennessee
Starting in New Orleans, with stops in Oak Alley, Baton Rouge, St Francisville, Natchez, Vicksburg, Cruising the Mississippi River, Memphis
2020 Sails: Oct 8, Oct 22, More...
Queen of the Mississippi Cruises7 Night - Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2020 Sails: Oct 24, Nov 28, Dec 5, 2021: Dec 20, Dec 28, More...
Queen of the Mississippi Cruises7 Night - Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2020 Sails: Oct 31, Nov 14, 2021: Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Nov 13, Nov 27, More...
American Duchess Cruises8 Night - A Taste of the True South Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Memphis, TN
2020 Sails: Nov 1, Nov 15, Nov 29, More...
America Cruises4 Night - Highlights of the Mississippi River roundtrip from New Orleans, LA
Starting in New Orleans, LA; with stops in Houmas House, LA; Baton Rouge, LA; Oak Alley, LA; New Orleans, LA
2020 Sails: Nov 12, Nov 16, Nov 20, Nov 24, 2021: Mar 21, Mar 25, Mar 29, Apr 2, Jun 29, Jul 3, Jul 7, More...
American Countess Cruises7 Night - Southern Sampler Roundtrip from New Orleans
Starting in New Orleans; with stops in St. Francisville; Natchez; Vicksburg; Baton Rouge; Nottoway Plantation; New Orleans
2020 Sails: Nov 29, More...
America Cruises7 Night - Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2020 Sails: Dec 12, Dec 20, Dec 28, 2021: Feb 28, Mar 7, Mar 14, Apr 6, Apr 13, Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, Jun 8, Jun 15, Jun 22, More...


New Orleans River Cruise Departures
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