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New Orleans River Cruise Departures

River Cruises that depart from North America: United States: Louisiana: New Orleans

River Cruises that visit New Orleans

See all Cruises that depart from New Orleans

Mississippi River Cruises

Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.

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American Countess Cruises8 Night - New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Aug 7, Sep 11, Oct 23, Dec 4, Dec 18, 2022: Mar 14, Mar 28, Apr 11, Oct 10, Nov 14, 2023: Mar 6, Mar 20, Apr 3, Apr 17, Sep 18, Nov 6, Nov 20, Dec 4, More...
American Queen Cruises8 Night - New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Aug 8, Sep 5, Sep 19, Oct 3, Oct 17, Nov 14, 2022: Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Sep 25, Nov 27, 2023: Feb 12, Feb 26, Mar 5, Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, More...
American Duchess Cruises8 Night - New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Aug 15, Sep 12, Oct 31, Nov 28, 2022: Mar 19, Apr 2, Apr 16, Apr 30, Jun 25, Oct 8, Dec 31, 2023: Mar 11, Mar 25, Apr 8, Apr 22, May 6, May 20, Jun 3, Jun 17, Sep 30, Nov 11, Nov 25, Dec 9, Dec 23, More...
America Cruises10 Night - Mississippi River Gateway Cruise from New Orleans, LA to St. Louis, MO
Starting in New Orleans, LA; with stops in Baton Rouge, LA; Natchez, MS; Vicksburg, MS; Memphis, TN; New Madrid, MO; Paducah, KY; St. Louis, MO
2021 Sails: Aug 25, 2022: Jul 10, Aug 24, 2023: Jul 9, Aug 23, More...
American Melody Cruises7 Night - New Orleans Roundtrip Cruise from New Orleans, LA
Starting in New Orleans, LA; with stops in Oak Alley, LA; Natchez, MS; Vicksburg, MS, St. Francisville, LA; Baton Rouge, LA; Houmas House, LA; New Orleans, LA
2021 Sails: Aug 27, More...
American Melody Cruises21 Night - Complete Mississippi River Cruise from New Orleans, LA to St. Paul, MN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Houmas House, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN; New Madrid, MO; Cape Girardeau, MO; Chester, IL; St. Louis, MO; Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2021 Sails: Sep 3, 2022: Jun 10, 2023: Jun 9, More...
American Jazz Cruises7 Night - New Orleans Roundtrip Cruise from New Orleans, LA
Starting in New Orleans, LA; with stops in Oak Alley, LA; Natchez, MS; Vicksburg, MS; St. Francisville, LA; Baton Rouge, LA; Houmas House, LA; New Orleans, LA
2021 Sails: Oct 3, 2022: Oct 2, Dec 4, Dec 11, 2023: Oct 1, Dec 3, Dec 10, More...
American Jazz Cruises7 Night - Lower Mississippi River Cruise from New Orleans, LA to Memphis, TN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Memphis, TN
2021 Sails: Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 20, 2022: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Oct 9, Oct 23, Nov 6, Nov 20, 2023: Feb 19, Mar 5, Mar 19, Apr 2, More...
Queen of the Mississippi Cruises4 Night - Highlights of the Mississippi River Cruise Roundtrip from New Orleans, LA
Starting in New Orleans, LA; with stops in Houmas House, LA; Baton Rouge, LA; Oak Alley, LA; New Orleans, LA
2021 Sails: Oct 19, 2022: Jul 23, More...
Queen of the Mississippi Cruises7 Night - New Orleans Roundtrip Cruise from New Orleans, LA
Starting in New Orleans, LA; with stops in Oak Alley, LA; Natchez, MS; Vicksburg, MS; St. Francisville, LA; Baton Rouge, LA; Houmas House, LA; New Orleans, LA
2021 Sails: Oct 23, Oct 30, Nov 6, Dec 20, Dec 28, 2022: Jul 16, Dec 21, Dec 29, 2023: Jul 15, More...


New Orleans River Cruise Departures

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