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New Orleans River Cruise Departures

River Cruises that depart from North America: United States: Louisiana: New Orleans

River Cruises that visit New Orleans

See all Cruises that depart from New Orleans

Mississippi River Cruises

Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.

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American Duchess Cruises8 Night - Lower Mississippi Cruise from New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Jan 3, Jan 17, Jan 31, Feb 28, Mar 14, Mar 21, Mar 28, May 23, Aug 15, Sep 12, Oct 31, Nov 28, More...
American Countess Cruises5 Night - Lower Mississippi Cruise Roundtrip from New Orleans
Starting in New Orleans, LA; with stops in White Castle, LA; St. Francisville, LA; Baton Rouge, LA
2021 Sails: Jan 17, More...
American Countess Cruises5 Night - Lower Mississippi Cruise Roundtrip from New Orleans
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Baton Rouge, LA
2021 Sails: Jan 21, Jan 25, Jan 29, Feb 2, More...
American Countess Cruises8 Night - Lower Mississippi Cruise from New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, TN; Memphis, TN
2021 Sails: Feb 6, Feb 20, Mar 6, Mar 20, Apr 17, May 1, May 15, May 29, Jun 26, Jul 10, Jul 24, Aug 7, Sep 11, Oct 23, More...
American Queen Cruises8 Night - Lower Mississippi River Cruise Roundtrip from New Orleans
Starting in New Orleans, LA; with stops in St. Francisville, LA; Natchez, MS; Vicksburg, MS; Baton Rouge, LA, Nottoway Plantation
2021 Sails: Feb 21, Feb 28, Dec 26, More...
America Cruises7 Night - Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2021 Sails: Feb 28, Mar 7, Mar 14, Apr 6, Apr 13, Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, Jun 8, Jun 15, Jun 22, Nov 6, Nov 21, 2022: Feb 20, Feb 27, Mar 6, Mar 13, Apr 5, Apr 12, Apr 19, More...
American Jazz Cruises7 Night - Lower Mississippi River Cruise from New Orleans, LA to Memphis, TN
Starting in New Orleans, LA; with stops in Oak Alley, LA; Baton Rouge, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Memphis, TN
2021 Sails: Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 20, 2022: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, More...
American Queen Cruises8 Night - Lower Mississippi Cruise from New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Aug 8, Sep 5, Sep 19, Oct 3, Oct 17, Nov 14, Nov 28, Dec 12, More...
America Cruises4 Night - Highlights of the Mississippi River roundtrip from New Orleans, LA
Starting in New Orleans, LA; with stops in Houmas House, LA; Baton Rouge, LA; Oak Alley, LA; New Orleans, LA
2021 Sails: Mar 21, Mar 25, Mar 29, Apr 2, Jun 29, Jul 3, Jul 7, Nov 13, Nov 17, 2022: Mar 20, Mar 24, Mar 28, Apr 1, Jun 28, Jul 2, Jul 6, Nov 12, Nov 16, More...
Queen of the Mississippi Cruises7 Night - Lower Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2021 Sails: Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Nov 13, Nov 27, More...


New Orleans River Cruise Departures

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