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New Orleans River Cruise Departures

River Cruises that depart from North America: United States: Louisiana: New Orleans

River Cruises that visit New Orleans

See all Cruises that depart from New Orleans

Mississippi River Cruises

Click on a river cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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American Duchess Cruises8 Night Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2019 Sails: Nov 24, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Dec 1, More...
American Harmony Cruises7 Night New Orleans to New Orleans Cruise New Orleans, Louisiana to New Orleans, Louisiana
Starting in New Orleans, with stops in Oak Alley, Natchez, Vicksburg, St Francisville, Baton Rouge, Houmas House, New Orleans
2019 Sails: Dec 5, Dec 12, Dec 20, Dec 28, 2021: Feb 14, Oct 3, More...
America Cruises7 Night Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2019 Sails: Dec 12, 2020: Feb 15, Feb 22, Feb 29, Mar 7, Mar 14, Jul 4, Jul 11, Jul 18, Dec 12, Dec 20, Dec 28, 2021: Feb 28, Mar 7, Mar 14, Apr 6, Apr 13, Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, More...
American Queen Cruises8 Night Plantation Holidays from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Dec 15, More...
America Cruises7 Night Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2019 Sails: Dec 20, 2020: Mar 21, Apr 4, Apr 18, May 9, May 23, Jun 6, More...
American Duchess Cruises8 Night American Christmas roundtrip New Orleans
Starting in New Orleans; with stops in Oak Alley, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Dec 22, More...
American Duchess Cruises5 Night New Year's Celebration roundtrip New Orleans
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; New Orleans
2019 Sails: Dec 29, More...
American Queen Cruises5 Night New Year's Celebration roundtrip New Orleans
Starting in New Orleans; with stops in Nottoway Plantation; Baton Rouge, LA; New Orleans
2019 Sails: Dec 29, More...
American Duchess Cruises8 Night A Taste of the True South Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Memphis, TN
2020 Sails: Jan 5, Feb 2, Mar 15, Mar 29, May 24, Jun 7, Aug 16, Nov 1, Nov 15, Nov 29, More...


New Orleans River Cruise Departures
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