New Orleans River Cruise Departures
River Cruises that depart from North America: United States: Louisiana: New Orleans
River Cruises that visit New Orleans
See all Cruises that depart from New Orleans
Mississippi River Cruises
River cruises by river name
7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 17, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 28, More...
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...
7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 25, More...
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Oct 18, Oct 24, Oct 30, Nov 5, Nov 11, Nov 17, Nov 23, Nov 29, 2027: Mar 27, Apr 2, Apr 8, More...8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...
River Cruises that depart from North America: United States: Louisiana: New Orleans
River Cruises that visit New Orleans
See all Cruises that depart from New Orleans
Mississippi River Cruises
Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 17, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 28, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 25, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Oct 18, Oct 24, Oct 30, Nov 5, Nov 11, Nov 17, Nov 23, Nov 29, 2027: Mar 27, Apr 2, Apr 8, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...
