Colon Cruises
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
76 Night - Central America Roundtrip from Southampton
Starting in Southampton, La Coruna, Las Palmas, Praia, Salvador, Rio De Janeiro, Ilhabela, Brazil, Buenos Aires, Montevideo, Port Stanley, Falkland Islands, Cruising by Antarctic Peninsula, Punta Arenas, Cruising Chilean Fjords, Valparaiso, Coquimbo, Iquique, Arica, Paracas, Callao, Amador, Panama Canal Transit, Puerto Limon, Colon, Cartagena De Indias, Colombia, Willemstad AN, Bequia, St Johns, Philipsburg, Ponta Delgada, Southampton
2026 Sails: Jan 28, More...
12 Night - Southern Caribbean with Panama
Starting in Fort Lauderdale, Florida, Aruba, Bonaire, Caribbean Netherlands, Cartagena CO, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 28, More...
21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 30, Feb 20, More...
13 Night - Journeys - Caribbean & Panama
Starting in Tampa, Fl, Grand Cayman, Cayman Islands, Limon, Costa Rica, Colon (Panama Canal), Panama, Aruba, Curacao, Amber Cove, Dominican Republic, Tampa, Fl
2026 Sails: Feb 1, More...
14 Night - Caribbean
Starting in New Orleans, La, Costa Maya, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Puerto Limon, Costa Rica, Colon, Panama, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, New Orleans, La
2026 Sails: Feb 1, More...
8 Night - In the Wake of the Spanish Armadas
Starting in Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon
2026 Sails: Feb 1, More...16 Night - Star Collector : Natural History Meets Ancient Mystery : Latin America & Beyond
Starting in Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon, Bocas del Toro, Isla San Andres, Roatan, Belize City, Costa Maya, Mexico, Cozumel, Mexico
2026 Sails: Feb 1, More...
14 Night - Journeys - Caribbean & Panama
Starting in Galveston, Tx, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Galveston, Tx
2026 Sails: Feb 2, More...
11 Night - Panama Canal & Southern Caribbean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal (Cruising), Colon, Panama, Oranjestad, Aruba, Willemstad AN, Curacao, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Feb 2, More...21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 8, Mar 1, More...
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
Click on a cruise ship itinerary that visits Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
76 Night - Central America Roundtrip from SouthamptonStarting in Southampton, La Coruna, Las Palmas, Praia, Salvador, Rio De Janeiro, Ilhabela, Brazil, Buenos Aires, Montevideo, Port Stanley, Falkland Islands, Cruising by Antarctic Peninsula, Punta Arenas, Cruising Chilean Fjords, Valparaiso, Coquimbo, Iquique, Arica, Paracas, Callao, Amador, Panama Canal Transit, Puerto Limon, Colon, Cartagena De Indias, Colombia, Willemstad AN, Bequia, St Johns, Philipsburg, Ponta Delgada, Southampton
2026 Sails: Jan 28, More...
12 Night - Southern Caribbean with PanamaStarting in Fort Lauderdale, Florida, Aruba, Bonaire, Caribbean Netherlands, Cartagena CO, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 28, More...
21 Night - Southern Caribbean & Panama Canal : Abc IslandsStarting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 30, Feb 20, More...
13 Night - Journeys - Caribbean & PanamaStarting in Tampa, Fl, Grand Cayman, Cayman Islands, Limon, Costa Rica, Colon (Panama Canal), Panama, Aruba, Curacao, Amber Cove, Dominican Republic, Tampa, Fl
2026 Sails: Feb 1, More...
14 Night - CaribbeanStarting in New Orleans, La, Costa Maya, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Puerto Limon, Costa Rica, Colon, Panama, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, New Orleans, La
2026 Sails: Feb 1, More...
8 Night - In the Wake of the Spanish ArmadasStarting in Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon
2026 Sails: Feb 1, More...
16 Night - Star Collector : Natural History Meets Ancient Mystery : Latin America & BeyondStarting in Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon, Bocas del Toro, Isla San Andres, Roatan, Belize City, Costa Maya, Mexico, Cozumel, Mexico
2026 Sails: Feb 1, More...
14 Night - Journeys - Caribbean & PanamaStarting in Galveston, Tx, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Galveston, Tx
2026 Sails: Feb 2, More...
11 Night - Panama Canal & Southern CaribbeanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal (Cruising), Colon, Panama, Oranjestad, Aruba, Willemstad AN, Curacao, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Feb 2, More...
21 Night - Panama Canal & Southern Caribbean : Abc IslandsStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 8, Mar 1, More...
