Colon Cruises
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
22 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Dec 23, More...
21 Night - Panama Canal & Southern Caribbean Holiday
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
14 Night - Panama Canal & Central America
Starting in West Palm Beach, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Cartagena CO, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
12 Night - Costa Rica, Panama Canal & Machu Picchu Cruise Tour
Starting in Lima, Peru, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Dec 31, 2027: Jan 14, Jan 28, More...11 Night - Caribbean and Antilles
Starting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2027 Sails: Jan 3, Jan 24, 2028: Jan 23, More...21 Night - Caribbean and Antilles
Starting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Willemstad AN, Oranjestad, Aruba, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Miami, Florida
2027 Sails: Jan 3, More...
10 Night - Secrets of Central America
Starting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2027 Sails: Jan 5, More...21 Night - Southern Caribbean & Panama Canal : Abc Islands
Starting in Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2027 Sails: Jan 8, More...12 Night - Costa Rica, Panama Canal & Machu Picchu Cruise Tour
Starting in Puerto Caldera, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon, Panama Canal, Lima, Peru
2027 Sails: Jan 12, Jan 26, More...
8 Night - Exploring Arenal Volcano, Pearl Islands and the Panama Canal
Starting in San Jose, Costa Rica / Arenal Volcano Area, Arenal Volcano Area, San Jose / Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2027 Sails: Jan 13, Jan 21, Nov 22, 2028: Jan 21, More...
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
Click on a cruise ship itinerary that visits Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
22 Night - Caribbean and AntillesStarting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2026 Sails: Dec 23, More...
21 Night - Panama Canal & Southern Caribbean HolidayStarting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
14 Night - Panama Canal & Central AmericaStarting in West Palm Beach, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Cartagena CO, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2026 Sails: Dec 27, More...
12 Night - Costa Rica, Panama Canal & Machu Picchu Cruise TourStarting in Lima, Peru, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2026 Sails: Dec 31, 2027: Jan 14, Jan 28, More...
11 Night - Caribbean and AntillesStarting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2027 Sails: Jan 3, Jan 24, 2028: Jan 23, More...
21 Night - Caribbean and AntillesStarting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Willemstad AN, Oranjestad, Aruba, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Miami, Florida
2027 Sails: Jan 3, More...
10 Night - Secrets of Central AmericaStarting in Puntarenas, Curu Wildlife Refuge, Drake Bay, Rio Esquinas, Coiba Island, Playa Muerto, Darien National Park, Pearls Islands, Pacheca Island, Crossing the Panama Canal, San Blas Islands, Fort San Lorenzo (Colon), Colon
2027 Sails: Jan 5, More...
21 Night - Southern Caribbean & Panama Canal : Abc IslandsStarting in Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2027 Sails: Jan 8, More...
12 Night - Costa Rica, Panama Canal & Machu Picchu Cruise TourStarting in Puerto Caldera, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon, Panama Canal, Lima, Peru
2027 Sails: Jan 12, Jan 26, More...
8 Night - Exploring Arenal Volcano, Pearl Islands and the Panama CanalStarting in San Jose, Costa Rica / Arenal Volcano Area, Arenal Volcano Area, San Jose / Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2027 Sails: Jan 13, Jan 21, Nov 22, 2028: Jan 21, More...
