Colon Cruises
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Feb 8, Mar 1, More...
7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Feb 15, Mar 22, Apr 5, More...
12 Night - Southern Caribbean with Panama
Starting in Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Falmouth, Jamaica, Limon, Costa Rica, Colon, Panama, Aruba, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
14 Night - Caribbean
Starting in New Orleans, La, Costa Maya, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Puerto Limon, Costa Rica, Colon, Panama, Cartagena CO, Montego Bay, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, New Orleans, La
2026 Sails: Feb 22, More...7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2026 Sails: Feb 22, Mar 1, More...
11 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Mar 1, More...21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Cozumel, Mexico, George Town, Cayman Islands, Ocho Rios, Jamaica, Willemstad AN, Curacao, Oranjestad, Aruba, Miami, Florida
2026 Sails: Mar 1, More...
11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Mar 4, More...
10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), Colon, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Mar 5, More...7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Mar 8, More...
Cruises that visit Central America: Panama: Colon
Cruises that depart from Colon
Click on a cruise ship itinerary that visits Colon (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Colon), please visit: Cruise Search or try our Virtual Cruise Advisor™.
12 Night - Panama Canal Discovery : Costa Rica & Greater AntillesStarting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Feb 8, Mar 1, More...
7 Night - Southern Caribbean CruiseStarting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Feb 15, Mar 22, Apr 5, More...
12 Night - Southern Caribbean with PanamaStarting in Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Falmouth, Jamaica, Limon, Costa Rica, Colon, Panama, Aruba, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
14 Night - CaribbeanStarting in New Orleans, La, Costa Maya, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Puerto Limon, Costa Rica, Colon, Panama, Cartagena CO, Montego Bay, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, New Orleans, La
2026 Sails: Feb 22, More...
7 Night - Southern Caribbean CruiseStarting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2026 Sails: Feb 22, Mar 1, More...
11 Night - Caribbean and AntillesStarting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Mar 1, More...
21 Night - Caribbean and AntillesStarting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Cozumel, Mexico, George Town, Cayman Islands, Ocho Rios, Jamaica, Willemstad AN, Curacao, Oranjestad, Aruba, Miami, Florida
2026 Sails: Mar 1, More...
11 Night - Panama Canal - MiamiStarting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Mar 4, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), Colon, San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2026 Sails: Mar 5, More...
7 Night - Southern Caribbean CruiseStarting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2026 Sails: Mar 8, More...
