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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

Star Clippers, Star Flyer
Star Flyer9 Night - Malta, Balearics & Spain
Starting in Malaga, Spain, Almeria, Spain, Cartagena ES, Ibiza / Balearic Islands, Spain, Mahon / Menorca / Balearic Islands, Spain, Cagliari / Sardinia, Italy, Gozo, Malta, Valletta, Malta
2026 Sails: Apr 10, 2027: Apr 16, More...
AmaWaterways, AmaVida
AmaVida7 Night - Flavors of Portugal & Spain
Starting in Vega de Terron, Barca dAlva, Pinhao, Regua, Entre-os-Rios, Porto
2026 Sails: Apr 11, Apr 25, May 9, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 26, Oct 10, 2027: Apr 10, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, More...
Carnival Cruise Lines, Carnival Glory
Carnival Glory13 Night - Journeys - Transatlantic
Starting in Barcelona, Spain, Alicante, Spain, Malaga, Spain, Gibraltar, Celebration Key, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna7 Night - Western Mediterranean from Santa Cruz de Tenerife to Savona
Starting in Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseille, France, Savona, Italy
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna6 Night - Western Mediterranean from Santa Cruz de Tenerife to Marseille
Starting in Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseille, France
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna5 Night - Western Mediterranean from Santa Cruz de Tenerife to Barcelona
Starting in Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain
2026 Sails: Apr 11, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna8 Night - Cruise from Santa Cruz de Tenerife to Rome (Civitavecchia)
Starting in Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseille, France, Savona, Italy, Civitavecchia / Rome
2026 Sails: Apr 11, More...
MSC Cruises, MSC Fantasia
MSC Fantasia1 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France
2026 Sails: Apr 11, More...
MSC Cruises, MSC Fantasia
MSC Fantasia5 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Barcelona, Spain
2026 Sails: Apr 11, Apr 16, More...
MSC Cruises, MSC Fantasia
MSC Fantasia2 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Apr 11, More...

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Spain Cruise Departures