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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

AmaWaterways Tours, AmaKristina Tours
AmaKristina Tours13 Night - Colors of Provence (Wine Cruise) with Barcelona Pre-Cruise and Paris Post-Cruise
Starting in Barcelona, Arles, Avignon, Viviers, Tournon, Vienne, Paris
2026 Sails: Mar 30, Nov 9, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Mar 30, Apr 3, Oct 6, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa12 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Marseille, Valencia, Cartagena ES, Spain, Malaga, Cadice, Lisbon, Alicante, Barcelona
2026 Sails: Mar 31, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa2 Night - Europe from Barcelona to Savona
Starting in Barcelona, Marseille, Savona
2026 Sails: Mar 31, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica5 Night - Western Mediterranean from Valencia
Starting in Valencia, Civitavecchia, Savona, Marseille, Valencia
2026 Sails: Apr 1, More...
Viking Ocean, Viking Jupiter
Viking Jupiter7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Apr 1, Oct 7, 2027: Jul 21, More...
Viking Ocean, Viking Jupiter
Viking Jupiter21 Night - Iconic Mediterranean Treasures
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 1, More...
Viking Ocean, Viking Jupiter
Viking Jupiter14 Night - Mediterranean Antiquities
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Apr 1, More...
Atlas Ocean Voyages, World Navigator
World Navigator7 Night - Tenerife Roundtrip
Starting in Santa Cruz de Tenerife, Puerto del Rosario (Fuerteventura), Agadir, Safi, Casablanca, Las Palmas (Gran Canaria), Santa Cruz de Tenerife
2026 Sails: Apr 2, More...
Explora Journeys, EXPLORA I
EXPLORA I11 Night - A Journey of Creative Spirit & Enchanting Canals
Starting in Barcelona, Port of Naples, La Valletta, Siracusa (Sicily), Corfu, Kotor, Brindisi, Split, Fusina (Venice)
2026 Sails: Apr 2, More...

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Spain Cruise Departures