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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Poesia
MSC Poesia14 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Funchal (Madeira Islands), Portugal, Philipsburg, St Maarten, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 9, More...
MSC Cruises, MSC Poesia
MSC Poesia32 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Funchal (Madeira Islands), Portugal, Philipsburg, St Maarten, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 9, More...
PONANT, Le Bougainville
Le Bougainville10 Night - Volcanic Islands and Historic Cities of the North Atlantic
Starting in Las Palmas de Gran Canaria, Canary Islands, Arrecife de Lanzarote, Canary Islands, Puerto del Rosario, Canary Islands, Santa Cruz de Tenerife, Funchal, Madeira, La Estaca, Canary Islands, San Sebastian de la Gomera, Canary Islands, Santa Cruz de La Palma, Las Palmas de Gran Canaria, Canary Islands
2026 Sails: Apr 9, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Apr 10, Apr 17, Apr 24, May 1, Oct 13, Oct 30, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna8 Night - Western Mediterranean from Las Palmas to Savona
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseille, France, Savona, Italy
2026 Sails: Apr 10, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna7 Night - Western Mediterranean from Las Palmas to Marseille
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseille, France
2026 Sails: Apr 10, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna6 Night - Western Mediterranean from Las Palmas to Barcelona
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain
2026 Sails: Apr 10, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna9 Night - Cruise from Las Palmas to Rome (Civitavecchia)
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Moroccan Sea Darkest Spot, Casablanca, Morocco, Barcelona, Spain, Marseilles, France, Savona, Italy, Civitavecchia / Rome
2026 Sails: Apr 10, More...
Regent Seven Seas, Seven Seas Splendor
Seven Seas Splendor9 Night - Plazas & Colonnades
Starting in Barcelona, Mahon, Minorca, Provence (Marseille), Monte Carlo, La Spezia (Cinque Terre), Ajaccio (Corsica), Cruising the Tyrrhenian Sea, Palermo (Sicily), Sorrento / Capri, Rome (Civitavecchia)
2026 Sails: Apr 10, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager7 Night - Elegant Shores
Starting in Barcelona, Palamos, Sete, Saint-Tropez, Cruising the Liguarian Sea, Tuscany (Livorno), Golfo Aranci (Sardinia), Rome (Civitavecchia)
2026 Sails: Apr 10, More...

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Spain Cruise Departures