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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Valencia
Starting in Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia
2026 Sails: Jul 8, Jul 15, Jul 22, Jul 29, Aug 5, Aug 12, More...
Silversea, Silver Shadow
Silver Shadow5 Night - Palma De Mallorca to Nice
Starting in Palma De Mallorca, Barcelona, Palamos, Sete, Marseille, Nice
2026 Sails: Jul 8, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - Mediterranean
Starting in Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain
2026 Sails: Jul 9, Aug 6, More...
Scenic Luxury, Scenic Eclipse II
Scenic Eclipse II11 Night - Wine & Culinary Delights of Spain, Portugal and France
Starting in Malaga, Spain, Tangier, Morocco, Seville, Spain, Portimao, Portugal, Lisbon, Portugal, Leixoes (Porto), Portugal, Ferrol, Spain, Aviles, Spain, Bilbao, Bordeaux, France
2026 Sails: Jul 9, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel7 Night - Greece, Malta & Turkey Cruise
Starting in Barcelona, Spain, Valletta, Malta, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Jul 11, Aug 8, More...
Virgin Voyages, Valiant Lady
Valiant Lady8 Night - Italy & French Riviera
Starting in Barcelona, Spain, Provence (Marseille), France, Nice (Villafranche), France, Rome (Civitavecchia), Italy, Amalfi Coast (Salerno), Italy, Catania, Sicily, Italy, Palermo, Sicily, Italy, Barcelona, Spain
2026 Sails: Jul 11, More...
Holland America, Oosterdam
Oosterdam14 Night - Malta, Greece & Amalfi Coast Collectors' Voyage
Starting in Barcelona, Spain, Valletta, Malta, Souda (Chania), Greece, Thira (Santorini), Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece, Kotor, Montenegro, Scenic cruising Bay of Kotor, Kerkira, (Corfu), Greece, Messina, Italy, Cruising Strait of Messina, Evening cruising Stromboli Volcano, Naples (Pompeii / Amalfi), Italy, Civitavecchia (Rome), Italy
2026 Sails: Jul 12, More...
Disney Cruise Line, Disney Dream
Disney Dream7 Night - Mediterranean Cruise from Barcelona
Starting in Barcelona, Naples, Civitavecchia, Livorno, Ajaccio, Barcelona
2026 Sails: Jul 13, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica4 Night - Cruise from Palma De Mallorca to Rome (Civitavecchia)
Starting in Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome)
2026 Sails: Jul 14, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox12 Night - Italy, France, Spain & Malta
Starting in Barcelona, Spain, Cannes, France, Florence / Pisa (La Spezia), Italy, Ajaccio, Corsica, France, Valletta, Malta, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy, Cagliari, Sardinia, Italy, Palma De Mallorca, Spain, Barcelona, Spain
2026 Sails: Jul 16, More...

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Spain Cruise Departures