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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Fortuna
Costa Fortuna5 Night - Canary Islands Roundtrip from Santa Cruz de Tenerife
Starting in Santa Cruz de Tenerife, La Gomera, Canary Islands, Fuerteventura, Canary Islands, Arrecife, Canary Islands, Atlantis Crest West, Las Palmas, Canary Islands, Santa Cruz de Tenerife
2026 Sails: Apr 6, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica6 Night - Mediterranean from Valencia to Savona
Starting in Valencia, Palma De Mallorca, Ibiza, La Spezia (Florence), Civitavecchia (Rome), Savona
2026 Sails: Apr 6, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica9 Night - Western Mediterranean from Valencia
Starting in Valencia, Palma De Mallorca, Ibiza, La Spezia (Florence), Civitavecchia (Rome), Savona, Marseille, Palma De Mallorca, Alicante
2026 Sails: Apr 6, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa3 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Apr 7, Apr 14, Apr 21, Apr 28, May 5, May 12, Oct 10, Oct 17, Oct 27, Nov 3, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Palma De Mallorca
Starting in Palma De Mallorca, Ibiza, La Spezia (Florence), Civitavecchia (Rome), Savona, Marseille, Palma De Mallorca
2026 Sails: Apr 7, More...
Scenic Luxury, Scenic Eclipse
Scenic Eclipse11 Night - Canary Islands, Morocco & Southern Spain
Starting in Santa Cruz de Tenerife, Canary Islands, Spain, Santa Cruz de la Palma, Canary Islands, Spain, Arrecife, Lanzarote, Canary Islands, Spain, Casablanca, Morocco, Cruising Guadalquivir River / Seville, Spain, Seville, Spain, Puerto Banus (Marbella), Spain, Malaga, Spain, Almeria, Spain, Ibiza, Spain, Barcelona, Spain
2026 Sails: Apr 7, More...
Windstar, Wind Star
Wind Star10 Night - Treasures of Southern Spain & Morocco
Starting in Malaga, Tangier, Gibraltar, Almeria, Spain, Cartagena ES, Valencia, Palma De Mallorca, Tarragona, Spain, Barcelona
2026 Sails: Apr 7, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra17 Night - Discover Cultural Treasures
Starting in Santa Cruz de Tenerife, Arrecife, Lanzarote, Spain, Casablanca, Morocco, Gibraltar, Spain, Malaga, Spain, Cartagena ES, Palma De Mallorca, Spain, Mahon, Menorca, Spain, Bonifacio, Corsica, France, Civitavecchia (Rome), Italy, Calvi, France, Livorno, Italy, Marina di Carrara, Italy, Porto Venere, Italy, Santa Margherita Ligure, Italy / Portofino, Italy, Monte Carlo, Monaco, Cannes, France
2026 Sails: Apr 8, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra10 Night - Highlights of Spain, Morocco & Italy
Starting in Santa Cruz de Tenerife, Arrecife, Lanzarote, Spain, Casablanca, Morocco, Gibraltar, Spain, Malaga, Spain, Cartagena ES, Palma De Mallorca, Spain, Mahon, Menorca, Spain, Bonifacio, Corsica, France, Civitavecchia (Rome), Italy
2026 Sails: Apr 8, More...

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Spain Cruise Departures