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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Orchestra
MSC Orchestra7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain, Barcelona, Spain
2026 Sails: Mar 29, Apr 5, Apr 12, More...
AmaWaterways Tours, AmaKristina Tours
AmaKristina Tours13 Night - Colors of Provence (Wine Cruise) with Barcelona Pre-Cruise and Paris Post-Cruise
Starting in Barcelona, Arles, Avignon, Vivigani, Tournon, Vienne, Paris
2026 Sails: Mar 30, Nov 9, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Mar 30, Apr 3, Oct 6, More...
Costa Cruise Lines, Costa Fortuna
Costa Fortuna7 Night - Canary Islands Roundtrip from Santa Cruz de Tenerife
Starting in Santa Cruz de Tenerife, La Gomera, Canary Islands, Fuerteventura, Canary Islands, Arrecife, Canary Islands, Atlantis Crest West, Las Palmas, Canary Islands, Funchal (Madeira), Canary Sea Darkest Spot, Santa Cruz de Tenerife
2026 Sails: Mar 30, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa12 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Marseille, Valencia, Cartagena ES, Spain, Malaga, Cadice, Lisbon, Alicante, Barcelona
2026 Sails: Mar 31, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa2 Night - Europe from Barcelona to Savona
Starting in Barcelona, Marseille, Savona
2026 Sails: Mar 31, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica5 Night - Western Mediterranean from Valencia
Starting in Valencia, Civitavecchia (Rome), Savona, Marseille, Valencia
2026 Sails: Apr 1, More...
Viking Ocean, Viking Jupiter
Viking Jupiter7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Apr 1, 2027: Jul 21, More...
Atlas Ocean Voyages, World Navigator
World Navigator7 Night - Tenerife Roundtrip
Starting in Santa Cruz de Tenerife, Puerto del Rosario (Fuerteventura), Agadir, Safi, Casablanca, Las Palmas (Gran Canaria), Santa Cruz de Tenerife
2026 Sails: Apr 2, More...

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Spain Cruise Departures