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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Norwegian Cruise Line, Norwegian Epic
Norwegian Epic7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Nice / Monaco (Villefranche), France, Provence, Marseille, France, Livorno / Florence / Pisa, Italy, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Sep 20, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel11 Night - Spain, Portugal & Morocco
Starting in Barcelona, Spain, Seville (Cadiz), Spain, Lisbon, Portugal, Madeira (Funchal), Portugal, Tangier, Morocco, Palma De Mallorca, Spain, Barcelona, Spain
2026 Sails: Sep 21, Oct 12, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema7 Night - Southern Europe Roundtrip from Barcelona
Starting in Barcelona, Spain, Marseille, France, Savona, Italy, Palma De Mallorca, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Sep 21, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema4 Night - Southern Europe from Barcelona to Palma De Mallorca
Starting in Barcelona, Spain, Marseille, France, Savona, Italy, Palma De Mallorca, Spain
2026 Sails: Sep 21, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema2 Night - Europe from Barcelona to Savona
Starting in Barcelona, Spain, Marseille, France, Savona, Italy
2026 Sails: Sep 21, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa14 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Palma De Mallorca, Malta / La Valletta, Thira (Santorini), Mykonos, Piraeus (Athens), Souda Bay (Crete), Messina (Taormina), Civitavecchia (Rome), Savona, Barcelona
2026 Sails: Sep 22, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Palma De Mallorca
Starting in Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca
2026 Sails: Sep 22, More...
AmaWaterways Tours, AmaVida Tours
AmaVida Tours13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Pinhao, Entre-os-Rios, Porto, Lisbon
2026 Sails: Sep 23, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Valencia
Starting in Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia
2026 Sails: Sep 23, More...
PONANT, Le Champlain
Le Champlain8 Night - Southern France and the Italian Riviera by Sea - with Smithsonian Journeys
Starting in Barcelona, Sete, Marseille, Nice, Santa Margherita Ligure, Porto Venere, Livorno, Bonifacio, Corsica, Civitavecchia (Rome)
2026 Sails: Sep 23, More...

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Spain Cruise Departures