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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Viking Ocean, Viking Saturn
Viking Saturn7 Night - Iconic Western Mediterranean
Starting in Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Oct 31, More...
Windstar, Wind Star
Wind Star10 Night - Treasures of Southern Spain & Morocco
Starting in Barcelona, Palma De Mallorca, Tarragona (Barcelona), Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 31, More...
Windstar, Wind Star
Wind Star24 Night - Star Collector : Classic Crossing to Spain & More
Starting in Barcelona, Palma De Mallorca, Tarragona (Barcelona), Valencia, Cartagena ES, Malaga, Tangier, Lisbon, Bridgetown, Barbados
2026 Sails: Oct 31, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Paris
2026 Sails: Nov 1, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Amboise, Paris
2026 Sails: Nov 1, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Paris
2026 Sails: Nov 1, Nov 8, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Amboise, Paris
2026 Sails: Nov 1, Nov 8, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Naples, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona
2026 Sails: Nov 1, More...
EXPLORA I16 Night - A Grand Journey of Lively Culture & Stunning Beaches
Starting in Barcelona, Cadiz, Funchal (Madeira), St Johns AG, Antigua, Road Bay, San Juan, Miami
2026 Sails: Nov 1, More...
EXPLORA I11 Night - A Journey Across Atlantic Horizons to the Caribbean
Starting in Barcelona, Cadiz, Funchal (Madeira), St Johns AG, Antigua
2026 Sails: Nov 1, More...

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Spain Cruise Departures