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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Ritz-Carlton, Evrima
Evrima7 Night - Barcelona / Lisbon
Starting in Barcelona, Palma de Mallorca, Mallorca, Balearic Islands, Ibiza, Balearic Islands, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 24, More...
Viking Ocean, Viking Star
Viking Star21 Night - Iconic Mediterranean Treasures
Starting in Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Oct 24, More...
Viking Ocean, Viking Star
Viking Star14 Night - Mediterranean Antiquities
Starting in Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Oct 24, More...
Viking Ocean, Viking Star
Viking Star7 Night - Iconic Western Mediterranean
Starting in Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Oct 24, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Paris
2026 Sails: Oct 25, Nov 1, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Paris
2026 Sails: Oct 25, Nov 1, Nov 8, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, Nov 8, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema6 Night - Western Mediterranean from Malaga
Starting in Malaga, Spain, Cartagena ES, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Oct 25, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Alicante, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Oct 25, More...

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Spain Cruise Departures