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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Magnifica
MSC Magnifica7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Nov 13, Nov 20, Nov 27, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit16 Night - Transatlantic from Gran Canaria to St Maarten (Philipsburg)
Starting in Las Palmas / Gran Canaria, Philipsburg
2026 Sails: Nov 13, More...
Star Clippers, Star Clipper
Star Clipper22 Night - Westbound Atlantic Ocean Crossing
Starting in Malaga, Spain, Casablanca, Morocco, Safi, Morocco, Arrecife / Lanzarote / Canary Islands, Spain, Santa Cruz de Tenerife, Las Palmas / Gran Canaria / Canary Islands, Spain, Santa Cruz de Tenerife, Bridgetown, Barbados
2026 Sails: Nov 13, More...
Star Clippers, Star Clipper
Star Clipper7 Night - Morocco & Canary Islands
Starting in Malaga, Spain, Casablanca, Morocco, Safi, Morocco, Arrecife / Lanzarote / Canary Islands, Spain, Santa Cruz de Tenerife, Las Palmas / Gran Canaria / Canary Islands, Spain
2026 Sails: Nov 13, More...
Star Clippers, Star Flyer
Star Flyer15 Night - Westbound Atlantic Ocean Crossing
Starting in Las Palmas, Gran Canaria / Canary Islands, Spain, San Sebastian / La Gomera, Spain, Philipsburg, St Maarten
2026 Sails: Nov 13, More...
Celebrity Cruises, Celebrity Infinity
Celebrity Infinity12 Night - Madeira, Canaries & Morocco
Starting in Barcelona, Spain, Lanzarote, Canary Islands, Tenerife, Canary Islands, Gran Canaria, Canary Islands, Madeira (Funchal), Portugal, Tangier, Morocco, Barcelona, Spain
2026 Sails: Nov 14, 2027: Jan 14, Feb 19, Mar 3, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda12 Night - Cruise from Barcelona to Las Palmas
Starting in Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife, Port Rosario (Fuerteventura), Arrecife (Lanzarote), Las Palmas (Gran Canaria)
2026 Sails: Nov 14, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda8 Night - Western Mediterranean from Barcelona to Santa Cruz de Tenerife
Starting in Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Nov 14, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda5 Night - Western Mediterranean from Barcelona to Santa Cruz de Tenerife
Starting in Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria)
2026 Sails: Nov 14, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia6 Night - Mediterranean
Starting in Valencia, Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Valencia, Spain
2026 Sails: Nov 14, More...

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Spain Cruise Departures