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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Port Rosario (Fuerteventura), Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Dec 20, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Port Rosario (Fuerteventura), Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Dec 21, More...
Viking Ocean, Viking Mira
Viking Mira7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sail the Mediterranean Sea, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Dec 23, More...
MSC Cruises, MSC Fantasia
MSC Fantasia7 Night - Canary Islands and Madeira
Starting in Arrecife De Lanzarote (Canary Islands), Spain, Las Palmas de Gran Canaria (Canary Islands), Spain, Santa Cruz de La Palma, Santa Cruz de Tenerife, Funchal (Madeira Islands), Portugal, Arrecife De Lanzarote (Canary Islands), Spain
2026 Sails: Dec 24, More...
MSC Cruises, MSC Fantasia
MSC Fantasia7 Night - Canary Islands and Madeira
Starting in Las Palmas de Gran Canaria (Canary Islands), Spain, Santa Cruz de La Palma, Santa Cruz de Tenerife, Funchal (Madeira Islands), Portugal, Arrecife De Lanzarote (Canary Islands), Spain, Las Palmas de Gran Canaria (Canary Islands), Spain
2026 Sails: Dec 25, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Port Rosario (Fuerteventura), Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Dec 27, More...
MSC Cruises, MSC Fantasia
MSC Fantasia7 Night - Canary Islands and Madeira
Starting in Santa Cruz de Tenerife, Funchal (Madeira Islands), Portugal, Arrecife De Lanzarote (Canary Islands), Spain, Las Palmas de Gran Canaria (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Santa Cruz de Tenerife
2026 Sails: Dec 27, More...
Viking Ocean, Viking Libra
Viking Libra15 Night - Malta, Morocco & the Mediterranean
Starting in Barcelona, Marseille, Corsica (Ajaccio), Rome (Civitavecchia), Sail the Mediterranean Sea, Valletta, Tunis (La Goulette), Sail the Mediterranean Sea, Algiers, Sail the Strait of Gibraltar, Casablanca, Seville (Cadiz), Granada (Malaga), Sail the Balearic Sea, Barcelona
2026 Sails: Dec 27, More...
Viking Ocean, Viking Saturn
Viking Saturn7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Dec 27, More...
Windstar, Wind Spirit
Wind Spirit10 Night - Hidden Gems of the Canary Islands & Madeira
Starting in Santa Cruz de Tenerife, Arrecife, Lanzarote, Funchal, Madeira, Porto Santo, Madeira, El Hierro / Puerto De La Estaca, San Sebastian De La Gomera, Santa Cruz de La Palma, Santa Cruz de Tenerife
2026 Sails: Dec 27, More...

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Spain Cruise Departures