Spain Cruise Departures
Cruises that depart from Europe: Spain
Cruises that visit Spain
See all River Cruises that depart from Spain
Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron
4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Oct 6, More...
7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, La Goulette, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 6, More...
7 Night - Mediterranean Holiday
Starting in Barcelona, Provence (Marseille), Cinque Terre (La Spezia), Ajaccio (Corsica), Cagliari (Sardinia), Palermo (Sicily), Naples / Pompeii, Rome (Civitavecchia)
2026 Sails: Oct 6, More...
7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Oct 7, 2027: Jun 9, Sep 25, More...
11 Night - Western Mediterranean from Alicante to Valletta
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta
2026 Sails: Oct 8, More...32 Night - Western Mediterranean from Alicante to Limassol
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol
2026 Sails: Oct 8, More...21 Night - Western Mediterranean from Alicante to Heraklion
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion
2026 Sails: Oct 8, More...63 Night - Western Mediterranean from Alicante to Southampton
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Oct 8, More...53 Night - Western Mediterranean from Alicante to Santa Cruz de Tenerife
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 8, More...42 Night - Western Mediterranean from Alicante to Athens (Piraeus)
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 8, More...
Cruises that depart from Europe: Spain
Cruises that visit Spain
See all River Cruises that depart from Spain
Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron
4 Night - Western Mediterranean from BarcelonaStarting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Oct 6, More...
7 Night - Western Mediterranean from BarcelonaStarting in Barcelona, La Goulette, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 6, More...
7 Night - Mediterranean HolidayStarting in Barcelona, Provence (Marseille), Cinque Terre (La Spezia), Ajaccio (Corsica), Cagliari (Sardinia), Palermo (Sicily), Naples / Pompeii, Rome (Civitavecchia)
2026 Sails: Oct 6, More...
7 Night - Iconic Western MediterraneanStarting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Oct 7, 2027: Jun 9, Sep 25, More...
11 Night - Western Mediterranean from Alicante to VallettaStarting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta
2026 Sails: Oct 8, More...
32 Night - Western Mediterranean from Alicante to LimassolStarting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol
2026 Sails: Oct 8, More...
21 Night - Western Mediterranean from Alicante to HeraklionStarting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion
2026 Sails: Oct 8, More...
63 Night - Western Mediterranean from Alicante to SouthamptonStarting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Oct 8, More...
53 Night - Western Mediterranean from Alicante to Santa Cruz de TenerifeStarting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens), Kalamata, Trapani, Tangier, Agadir, Santa Cruz de Tenerife
2026 Sails: Oct 8, More...
42 Night - Western Mediterranean from Alicante to Athens (Piraeus)Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta, Brindisi, Split, Koper, Kotor, Cruising Bay of Kotor, Kotor, Cruising Bay of Kotor, Dubrovnik, Croatia, Kerkira, Heraklion, Ermoupolis, Temple of Poseidon, Pass Tourlitis Lighthouse, Kavala, Pass Mount Athos, Mytilene, Samos, Rhodes, Limassol, Alexandria EG, Marmaris, Istanbul, Piraeus (for Athens)
2026 Sails: Oct 8, More...
