Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Norwegian Line Tours, Norwegian Dawn Tours

10 Night - Explore Barcelona Pre Cruisetour
Starting in At Hotel, Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Oct 8, More...

Carnival Cruise Lines, Carnival Freedom

8 Night - Mediterranean
Starting in Barcelona, Spain, Marseilles (Provence), France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy, Naples (Amalfi / Pompeii), Italy, Valletta, Malta, Barcelona, Spain
2026 Sails: Oct 9, More...

Costa Cruise Lines, Costa Diadema

10 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Spain, Tangier, Morocco, Casablanca, Morocco, Cadiz, Spain, Gibraltar (UK), Malaga, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Oct 9, More...

Celebrity Cruises, Celebrity Equinox

10 Night - Italy, France & Malta Cruise
Starting in Barcelona, Spain, Valletta, Malta, Sicily (Messina), Italy, Naples, Italy, Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Barcelona, Spain
2026 Sails: Oct 10, More...

Costa Cruise Lines, Costa Fascinosa

3 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Oct 10, Oct 17, Oct 27, Nov 3, More...

Princess Cruises, Sun Princess

14 Night - Mediterranean with Greece, Italy & Turkey
Starting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 10, 2027: Sep 26, Oct 17, More...

Princess Cruises, Sun Princess

7 Night - Western Mediterranean with Italy
Starting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Oct 10, 2027: Sep 26, Oct 17, More...

Princess Cruises, Sun Princess

21 Night - The Best of the Mediterranean
Starting in Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Oct 10, More...

Norwegian Cruise Line, Norwegian Dawn

7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Oct 11, More...

Virgin Voyages, Scarlet Lady

14 Night - Spanish Isles & Transatlantic Miles
Starting in Barcelona, Spain, Casablanca, Morocco, Gran Canaria, Las Palmas, Spain, Santa Cruz de Tenerife, Miami
2026 Sails: Oct 11, More...

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