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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Sinfonia
MSC Sinfonia7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain, Barcelona, Spain
2026 Sails: Nov 8, Nov 22, More...
Silversea, Silver Ray
Silver Ray10 Night - Barcelona to Barcelona
Starting in Barcelona, Marseille, Palma De Mallorca, Gibraltar, Malaga (Costa del Sol), Cartagena ES, Spain, Valencia, Barcelona
2026 Sails: Nov 8, More...
AmaWaterways Tours, AmaKristina Tours
AmaKristina Tours13 Night - Colors of Provence (Wine Cruise) with Barcelona Pre-Cruise and Paris Post-Cruise
Starting in Barcelona, Arles, Avignon, Viviers, Tournon, Vienne, Lyon, Paris
2026 Sails: Nov 9, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda5 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Nov 9, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda3 Night - Europe from Barcelona to Savona
Starting in Barcelona, Civitavecchia (Rome), Savona
2026 Sails: Nov 9, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean Roundtrip from Palma De Mallorca
Starting in Palma De Mallorca, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona, Palma De Mallorca
2026 Sails: Nov 9, More...
Celebrity Cruises, Celebrity Eclipse
Celebrity Eclipse14 Night - Spain & Bermuda Transatlantic
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Cartagena ES, Malaga, Spain, Gibraltar, United Kingdom, Royal Naval Dockyard, Bermuda, Fort Lauderdale, Florida
2026 Sails: Nov 10, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema13 Night - Transatlantic from Las Palmas
Starting in Las Palmas (Gran Canaria), Santa Cruz de Tenerife, Mindelo (Sao Vicente), Maceio, Salvador Bahia, Rio De Janeiro, Santos (Sao Paulo)
2026 Sails: Nov 10, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema12 Night - Transatlantic from Las Palmas
Starting in Las Palmas (Gran Canaria), Santa Cruz de Tenerife, Mindelo (Sao Vicente), Maceio, Salvador Bahia, Rio De Janeiro
2026 Sails: Nov 10, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Nov 10, More...

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Spain Cruise Departures