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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Port Rosario (Fuerteventura), Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Dec 28, More...
Explora Journeys, EXPLORA II
EXPLORA II17 Night - An Extended Journey from a Riviera New Year to the Mediterranean's Deep Soul
Starting in Barcelona, Palma De Mallorca, Palamos, Port of Fecamp, Villefranche-Sur-Mer (Nice), Genoa, Livorno (Florence), Civitavecchia (Rome), Port of Naples, Siracusa (Sicily), Bari, La Valletta, Tunis / La Goulette, Palermo (Sicily), Civitavecchia (Rome)
2026 Sails: Dec 28, More...
Explora Journeys, EXPLORA II
EXPLORA II7 Night - A Journey of Riviera Lights & New Year Celebrations
Starting in Barcelona, Palma De Mallorca, Palamos, Port of Fecamp, Villefranche-Sur-Mer (Nice), Genoa, Livorno (Florence), Civitavecchia (Rome)
2026 Sails: Dec 28, More...
MSC Cruises, MSC Magnifica
MSC Magnifica10 Night - Mediterranean
Starting in Barcelona, Spain, Cadiz (Seville), Spain, Malaga (Granada), Spain, Alicante, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Dec 28, More...
Windstar, Star Explorer
Star Explorer9 Night - Southern Spain Winter Escapes
Starting in Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2026 Sails: Dec 28, 2027: Jan 6, Feb 14, 2028: Jan 4, Jan 13, More...
Azamara Onward10 Night - Mediterranean New Year's Cruise : Casablanca, Cadiz & Seville
Starting in Barcelona, Cartagena ES, Malaga, Casablanca, Tangier, Cadiz, Seville, Lisbon
2026 Sails: Dec 29, More...
Viking Ocean, Viking Vela
Viking Vela15 Night - Malta, Morocco & the Mediterranean
Starting in Barcelona, Marseille, Corsica (Ajaccio), Sail the Tyrrhenian Sea, Sicily (Messina), Valletta, Tunis (La Goulette), Sail the Mediterranean Sea, Algiers, Sail the Strait of Gibraltar, Casablanca, Seville (Cadiz), Granada (Malaga), Sail the Balearic Sea, Barcelona
2026 Sails: Dec 29, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Iconic Western Mediterranean
Starting in Barcelona, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Dec 30, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda8 Night - Western Mediterranean from Las Palmas
Starting in Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife, Port Rosario (Fuerteventura), Arrecife (Lanzarote), Las Palmas (Gran Canaria)
2026 Sails: Dec 31, More...
MSC Cruises, MSC Fantasia
MSC Fantasia7 Night - Canary Islands and Madeira
Starting in Arrecife De Lanzarote (Canary Islands), Spain, Las Palmas de Gran Canaria (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Santa Cruz de Tenerife, Puerto Del Rosario / Fuerteventura, Spain, Funchal (Madeira Islands), Portugal, Arrecife De Lanzarote (Canary Islands), Spain
2026 Sails: Dec 31, More...

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Spain Cruise Departures