Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Norwegian Line Tours, Norwegian Dawn Tours

10 Night - a Glimpse of Lisbon Pre Cruisetour
Starting in At Hotel, Barcelona (Tarragona), Spain, Cadiz / Seville, Spain, Motril, Spain, Gibraltar, Ibiza, Spain, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Oct 1, More...

Celebrity Cruises, Celebrity Xcel

10 Night - Italy & French Riviera
Starting in Barcelona, Spain, Naples, Italy, Sicily (Messina), Italy, Rome (Civitavecchia), Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Barcelona, Spain
2026 Sails: Oct 2, More...

Oceania Cruises, Oceania Marina

9 Night - Around Iberia
Starting in Bilbao, La Coruna, Oporto, Lisbon, Portimao, Gibraltar, Seville (Cadiz), Malaga, Alicante, Barcelona (Tarragona)
2026 Sails: Oct 2, More...

Scenic Luxury, Scenic Eclipse II

11 Night - Iberian Discovery : Spain and Portugal with Morocco
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Ibiza, Spain, Cartagena ES, Malaga, Spain, Puerto Banus (Marbella), Spain, Gibraltar, United Kingdom / Transit Strait of Gibraltar, Tangier, Morocco, Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Oct 3, More...

Costa Cruise Lines, Costa Diadema

5 Night - Cruise from Malaga to Barcelona
Starting in Malaga, Spain, Cartagena ES, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Oct 4, More...

Norwegian Cruise Line, Norwegian Dawn

7 Night - Europe
Starting in Barcelona (Tarragona), Spain, Cadiz / Seville, Spain, Motril, Spain, Gibraltar, Ibiza, Spain, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Oct 4, More...

Princess Tours, Sun Princess Tours

27 Night - Highlights of Spain - Tour 2C
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Oct 4, More...

Princess Tours, Sun Princess Tours

20 Night - Highlights of Spain - Tour 2B
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Oct 4, More...

Princess Tours, Sun Princess Tours

13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Oct 4, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 5, More...

<= Back

More =>