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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Favolosa
Costa Favolosa3 Night - Transatlantic from Barcelona
Starting in Barcelona, Savona, Marseille, Barcelona
2026 Sails: May 3, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona
2026 Sails: May 3, May 10, May 17, May 24, May 31, Jul 26, Aug 2, Aug 9, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana6 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille
2026 Sails: May 3, More...
Explora Journeys, EXPLORA I
EXPLORA I5 Night - A Journey Through Iberian Soul & Moorish Echoes
Starting in Barcelona, Cadiz, Tangier, Motril, Cartagena ES
2026 Sails: May 3, More...
Explora Journeys, EXPLORA I
EXPLORA I17 Night - An Extended Journey Through Architectural Wonders & Spectacular Landscapes
Starting in Barcelona, Cadiz, Tangier, Motril, Cartagena ES, Saint-Tropez, Monte Carlo, Livorno (Florence), Civitavecchia (Rome), Sorrento, Palermo (Sicily), Tunis / La Goulette, Ibiza, Mahon (Menorca), Barcelona
2026 Sails: May 3, More...
Explora Journeys, EXPLORA I
EXPLORA I10 Night - A Journey of Unique Architecture Seamlessely Blending Culture & Scenic Beauty
Starting in Barcelona, Cadiz, Tangier, Motril, Cartagena ES, Saint-Tropez, Monte Carlo, Livorno (Florence), Civitavecchia (Rome)
2026 Sails: May 3, More...
Norwegian Cruise Line, Norwegian Epic
Norwegian Epic7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Provence, Marseille, France, Nice / Monaco (Villefranche), France, Livorno / Florence / Pisa, Italy, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: May 3, May 31, Jun 14, Jun 28, Jul 12, Jul 26, Aug 9, Oct 4, Oct 18, More...
Ritz-Carlton, Ilma
Ilma8 Night - Barcelona / Rome (Civitavecchia)
Starting in Barcelona, Palma de Mallorca, Mallorca, Balearic Islands, Saint-Tropez, Cannes, Monte Carlo, Portofino, Livorno, Rome (Civitavecchia)
2026 Sails: May 3, More...
Scenic Luxury, Scenic Eclipse II
Scenic Eclipse II12 Night - Jewels of Spain and Morocco
Starting in Santa Cruz de Tenerife, Canary Islands, Spain, Santa Cruz de la Palma, Canary Islands, Spain, Arrecife, Lanzarote, Canary Islands, Spain, Casablanca, Morocco, Tangier, Morocco, Seville, Spain, Puerto Banus (Marbella), Spain, Oran, Algeria, Ibiza, Spain, Palma De Mallorca, Spain, Barcelona, Spain
2026 Sails: May 3, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, La Goulette, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: May 4, More...

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Spain Cruise Departures