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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, Nov 8, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema6 Night - Western Mediterranean from Malaga
Starting in Malaga, Spain, Cartagena ES, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Oct 25, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Alicante, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Oct 25, More...
PONANT, Le Laperouse
Le Laperouse7 Night - The Canaries, Lands of Contrast
Starting in Las Palmas de Gran Canaria, Canary Islands, Arrecife de Lanzarote, Canary Islands, Puerto del Rosario, Canary Islands, Los Cristianos, Canary islands, Santa Cruz de La Palma, La Estaca, Canary Islands, San Sebastian de la Gomera, Canary Islands, Las Palmas de Gran Canaria, Canary Islands
2026 Sails: Oct 25, More...
Princess Tours, Sun Princess Tours
Sun Princess Tours21 Night - Highlights of Spain - Tour 2D
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
Royal Caribbean, Legend of the Seas
Legend of the Seas13 Night - Spanish Transatlantic Cruise
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Malaga, Spain, Seville (Cadiz), Spain, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit8 Night - Sunshine and Culture Indulgence
Starting in Palma De Mallorca, Barcelona, Tarragona, Valencia, Cartagena, Malaga
2026 Sails: Oct 25, More...
AmaWaterways Tours, AmaKristina Tours
AmaKristina Tours13 Night - Colors of Provence with Barcelona Pre-Cruise and Paris Post-Cruise
Starting in Barcelona, Nimes, Arles, Avignon, Arles, Avignon, Vivigani, Tournon, Vienne, Limon, Villefranche-sur-Saone, Limon, Paris
2026 Sails: Oct 26, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 26, More...
Regent Seven Seas, Seven Seas Mariner
Seven Seas Mariner14 Night - Moonlight Over Bermuda
Starting in Barcelona, Cruising the Mediterranean Sea, Malaga, Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Hamilton, Cruising the Atlantic Ocean, Miami
2026 Sails: Oct 26, More...

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Spain Cruise Departures