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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Valencia
Starting in Valencia, Olbia, Civitavecchia, Savona, Toulon / La Seyne-sur-Mer, Palma De Mallorca, Alicante
2026 Sails: May 27, Aug 12, More...
Explora Journeys, EXPLORA I
EXPLORA I13 Night - An Extended Journey of Splendid Coastlines & Formula 1 Action
Starting in Barcelona, Mahon (Menorca), Alghero (Sardinia), Cannes, Saint-Tropez, Civitavecchia (Rome), Monte Carlo, Civitavecchia (Rome)
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I12 Night - An Extended Journey from Mediterranean Radiance to a Legendary Monaco Race Weekend
Starting in Barcelona, Mahon (Menorca), Alghero (Sardinia), Cannes, Saint-Tropez, Civitavecchia (Rome), Monte Carlo
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I6 Night - A Journey from Catalan Colours to Roman Grandeur
Starting in Barcelona, Mahon (Menorca), Alghero (Sardinia), Cannes, Saint-Tropez, Civitavecchia (Rome)
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I7 Night - A Journey of Authentic Flavours & Glittering Shorelines
Starting in Barcelona, Mahon (Menorca), Alghero (Sardinia), Cannes, Saint-Tropez, Civitavecchia (Rome), Monte Carlo
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I19 Night - An Extended Journey from Riviera Icons to Grand Prix Glamour
Starting in Barcelona, Mahon (Menorca), Alghero (Sardinia), Cannes, Saint-Tropez, Civitavecchia (Rome), Monte Carlo, Civitavecchia (Rome), Sorrento, Giardini Naxos, La Valletta, Palma De Mallorca, Barcelona
2026 Sails: May 27, More...
Azamara Onward14 Night - Grand Prix Cruise : Malaga, Marseille & Rome
Starting in Gran Canaria, Canary Islands, Lanzarote, Canary Islands, Agadir, Casablanca, Gibraltar, Malaga, Almeria, Provence (Marseille), St Tropez, Villefranche, Florence / Pisa (Livorno), Rome (Civitavecchia), Barcelona
2026 Sails: May 28, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa9 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia, Napoli, Palermo, La Goulette, Malta / La Valletta, Catania, Taranto
2026 Sails: May 29, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa8 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia, Napoli, Palermo, La Goulette, Malta / La Valletta, Catania
2026 Sails: May 29, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa12 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia, Napoli, Palermo, La Goulette, Malta / La Valletta, Catania, Taranto, Argostoli / Cephalonia, Mykonos, Athens (Piraeus)
2026 Sails: May 29, More...

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Spain Cruise Departures