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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Palma De Mallorca, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Nov 30, Dec 7, Dec 14, Dec 21, Dec 28, 2027: Jan 4, Jan 11, Jan 18, Jan 25, Feb 1, Feb 8, Feb 15, Feb 22, Mar 1, Mar 8, Mar 15, Mar 22, More...
Fred Olsen Cruise Lines, Balmoral
Balmoral10 Night - Atlantic from Santa Cruz de Tenerife to Southampton
Starting in Santa Cruz de Tenerife, Las Palmas, Arrecife, Funchal, Lisbon, Matosinhos, Southampton
2026 Sails: Nov 30, More...
Silversea, Silver Nova
Silver Nova9 Night - Barcelona to Lisbon
Starting in Barcelona, Valencia, Malaga (Costa del Sol), Cadiz, Gibraltar, Casablanca, Lisbon
2026 Sails: Nov 30, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean Roundtrip from Palma De Mallorca
Starting in Palma De Mallorca, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona, Palma De Mallorca
2026 Sails: Dec 1, Dec 8, Dec 15, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Jan 19, Jan 26, Feb 2, Feb 9, Feb 16, Feb 23, Mar 2, Mar 9, Mar 16, Mar 23, More...
Viking Ocean, Viking Neptune
Viking Neptune7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Dec 1, 2027: Feb 26, Dec 22, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Las Palmas
Starting in Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife, Arrecife (Lanzarote), Port Rosario (Fuerteventura), Las Palmas (Gran Canaria)
2026 Sails: Dec 3, More...
PONANT, Le Champlain
Le Champlain10 Night - Volcanic Landscapes from Canary Islands to Cape Verde
Starting in Las Palmas de Gran Canaria, Canary Islands, Arrecife de Lanzarote, Canary Islands, Puerto del Rosario, Canary Islands, Santa Cruz de Tenerife, San Sebastian de la Gomera, Canary Islands, Mindelo, Praia, Dakar
2026 Sails: Dec 3, More...
Azamara Quest13 Night - Transatlantic Cruise : Malaga, San Juan & Miami
Starting in Malaga, Tangier, San Juan, Miami, Florida
2026 Sails: Dec 4, More...
MSC Cruises, MSC Magnifica
MSC Magnifica4 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Dec 4, More...
MSC Cruises, MSC World Asia
MSC World Asia7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Dec 4, Dec 11, Dec 18, Dec 25, 2027: Jan 1, Jan 8, Jan 15, Jan 22, Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, Mar 12, Mar 19, Mar 26, Apr 2, Apr 9, More...

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Spain Cruise Departures