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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Toscana
Costa Toscana8 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Palma De Mallorca, Alicante, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Nov 22, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana6 Night - Europe from Barcelona to Savona
Starting in Barcelona, Palma De Mallorca, Alicante, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Nov 22, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana5 Night - Southern Europe from Barcelona to Rome (Civitavecchia)
Starting in Barcelona, Palma De Mallorca, Alicante, Palermo, Civitavecchia (Rome)
2026 Sails: Nov 22, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana4 Night - Western Mediterranean from Barcelona to Palermo
Starting in Barcelona, Palma De Mallorca, Alicante, Palermo
2026 Sails: Nov 22, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Port Rosario (Fuerteventura), Arrecife (Lanzarote), Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Nov 23, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana8 Night - Western Mediterranean Roundtrip from Palma De Mallorca
Starting in Palma De Mallorca, Alicante, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona, Palma De Mallorca
2026 Sails: Nov 23, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica3 Night - Europe from Barcelona to Savona
Starting in Barcelona, Civitavecchia (Rome), Savona
2026 Sails: Nov 24, More...
Oceania Marina15 Night - Fall Caribbean Passage
Starting in Barcelona, Valencia, Alicante, Malaga, Funchal (Madeira), San Juan, Puerto Plata, Dominican Republic, Miami
2026 Sails: Nov 25, More...
PONANT, Le Champlain
Le Champlain8 Night - Atlantic Odyssey from the Iberian Peninsula to the Canary Islands
Starting in Malaga, Tangier, Casablanca, Funchal, Madeira, Santa Cruz de La Palma, Arrecife de Lanzarote, Canary Islands, Las Palmas de Gran Canaria, Canary Islands
2026 Sails: Nov 25, More...
Viking Ocean, Viking Mira
Viking Mira7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Nov 25, More...

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Spain Cruise Departures