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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Oceania Cruises, Oceania Nautica
Oceania Nautica10 Night - Iberia Circumnavigation
Starting in Barcelona, Palma De Mallorca, Cartagena ES, Malaga, Casablanca, Seville (Cadiz), Portimao, Lisbon, Gijon, Spain, Bilbao
2026 Sails: Aug 20, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity9 Night - Europe & Mediterranean
Starting in Barcelona, Toulon, Monte Carlo, Livorno (Tuscany), Porto Santo Stefano, Olbia (Sardinia), Trapani, Salerno, Civitavecchia (Rome)
2026 Sails: Aug 21, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity3 Night - Europe & Mediterranean
Starting in Barcelona, Toulon, Monte Carlo
2026 Sails: Aug 21, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit11 Night - Songs 'N' Sail
Starting in Palma De Mallorca, Ibiza City / Ibiza, Mahon / Menorca, Alghero / Sardinia, Porto Cervo / Sardinia, Ajaccio / Corsica, Olbia / Sardinia
2026 Sails: Aug 22, More...
Norwegian Cruise Line, Norwegian Epic
Norwegian Epic7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Provence, Marseille, France, Cannes, France, Livorno / Florence / Pisa, Italy, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Aug 23, Sep 6, More...
Princess Tours, Sun Princess Tours
Sun Princess Tours13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Aug 23, More...
Regent Seven Seas, Seven Seas Navigator
Seven Seas Navigator9 Night - Miro to Michelangelo
Starting in Barcelona, Sete, Toulon, Portofino, Tuscany (Livorno), Rome (Civitavecchia), Sorrento / Capri, Cruising the Mediterranean Sea, Palma De Mallorca, Barcelona
2026 Sails: Aug 24, More...
Silversea, Silver Ray
Silver Ray6 Night - Barcelona to Monte Carlo
Starting in Barcelona, Marseille, Portofino, Livorno (Tuscany), Porto Santo Stefano, Ajaccio (Corsica), Monte Carlo
2026 Sails: Aug 24, More...
Norwegian Line Tours, Norwegian Dawn Tours
Norwegian Dawn Tours10 Night - Explore Barcelona Pre Cruisetour
Starting in At Hotel, Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Aug 27, Sep 10, More...
MSC Cruises, MSC Opera
MSC Opera10 Night - Mediterranean
Starting in Alicante, Spain, Mahon Minorque, Olbia, Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Malaga (Granada), Spain, Cadiz (Seville), Spain, Lisbon (Cascais), Portugal, Alicante, Spain
2026 Sails: Aug 28, More...

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Spain Cruise Departures