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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Regent Seven Seas, Seven Seas Navigator
Seven Seas Navigator12 Night - Spanish & Moroccan Delights
Starting in Barcelona, Alicante, Cruising the Mediterranean Sea, Malaga, Gibraltar, Casablanca, Agadir, Arrecife (Lanzarote), Santa Cruz de Tenerife, Funchal (Madeira), Cruising the Atlantic Ocean, Lisbon
2026 Sails: Nov 11, More...
Viking Ocean, Viking Vesta
Viking Vesta7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Nov 11, More...
MSC Cruises, MSC Seaview
MSC Seaview2 Night - Mediterranean
Starting in Tarragona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Nov 12, More...
MSC Cruises, MSC Virtuosa
MSC Virtuosa4 Night - Northern Europe
Starting in Malaga (Granada), Spain, Alicante, Spain, Palma De Mallorca (Balearic Islands), Spain, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Nov 12, More...
MSC Cruises, MSC World Europa
MSC World Europa2 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Nov 12, More...
MSC Cruises, MSC World Europa
MSC World Europa6 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, La Spezia (Cinque Terre), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Nov 12, More...
MSC Cruises, MSC World Europa
MSC World Europa5 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, La Spezia (Cinque Terre), Italy, Marseille (Provence), France
2026 Sails: Nov 12, More...
Windstar, Star Legend
Star Legend22 Night - Star Collector : Caribbean Beats & Transatlantic Treats
Starting in Malaga, Tangier, Casablanca, Funchal, Madeira, Bridgetown, Barbados, Anse Mitan, Martinique, Rodney Bay, Castries, St Lucia, Sunset Cruising Pitons, Mayreau, St Georges, Grenada, Bequia, Bridgetown, Barbados
2026 Sails: Nov 12, More...
Windstar, Star Legend
Star Legend15 Night - Ocean Crossing
Starting in Malaga, Tangier, Casablanca, Funchal, Madeira, Bridgetown, Barbados
2026 Sails: Nov 12, More...
MSC Cruises, MSC Magnifica
MSC Magnifica7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Nov 13, Nov 20, Nov 27, More...

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Spain Cruise Departures