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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Diadema
Costa Diadema5 Night - Cruise from Malaga to Barcelona
Starting in Malaga, Spain, Cartagena ES, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Oct 4, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn7 Night - Europe
Starting in Barcelona (Tarragona), Spain, Cadiz / Seville, Spain, Motril, Spain, Gibraltar, Ibiza, Spain, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Oct 4, More...
Princess Tours, Sun Princess Tours
Sun Princess Tours27 Night - Highlights of Spain - Tour 2C
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Oct 4, More...
Princess Tours, Sun Princess Tours
Sun Princess Tours13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Oct 4, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 5, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Oct 6, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, La Goulette (Tunis), Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Oct 6, Oct 13, Oct 20, Oct 27, Nov 3, More...
Oceania Cruises, Oceania Insignia
Oceania Insignia7 Night - Mediterranean Holiday
Starting in Barcelona, Provence (Marseille), Cinque Terre (La Spezia), Ajaccio (Corsica), Cagliari (Sardinia), Palermo (Sicily), Naples / Pompeii, Rome (Civitavecchia)
2026 Sails: Oct 6, More...
Viking Ocean, Viking Jupiter
Viking Jupiter7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Oct 7, 2027: Jun 9, Sep 25, More...
Fred Olsen Cruise Lines, Balmoral
Balmoral11 Night - Western Mediterranean from Alicante to Valletta
Starting in Alicante, Mahon, Savona, La Spezia, Bastia, Propriano, Pass Amalfi Coast, Salerno, Pass Maratea Coast, Cruising by Stromboli, Cruising the Strait of Messina, Valletta
2026 Sails: Oct 8, More...

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Spain Cruise Departures