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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Silversea, Silver Muse
Silver Muse10 Night - Barcelona to Lisbon
Starting in Barcelona, Valencia, Cartagena ES, Spain, Malaga (Costa del Sol), Gibraltar, Cadiz, Tangier, Casablanca, Lisbon
2026 Sails: Aug 10, More...
Virgin Voyages, Scarlet Lady
Scarlet Lady12 Night - Total Eclipse of the (Med)
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Ibiza, Spain, Cannes, France, Ajaccio, Corsica, France, La Spezia, Italy, Salerno (Amalfi Coast), Italy, Catania, Sicily, Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 10, More...
PONANT, Le Dumont-d'Urville
Le Dumont-d'Urville8 Night - A Solar Eclipse at Sea : Voyage Across the Western Mediterranean - with Smithsonian Journeys
Starting in Barcelona, Palma de Mallorca, Balearic Islands, Mahon, Balearic Islands, Alghero, Sardinia, LIle-Rousse, Corsica, Portoferraio, Elba, Porto Ercole, Portofino, Nice
2026 Sails: Aug 11, More...
Azamara Cruises, Azamara Onward
Azamara Onward9 Night - Italy, France & Spain Cruise : Rosas, Marseille & Florence
Starting in Barcelona, Rosas, Provence (Marseille), Sanary-sur-mer, Monte Carlo, Florence / Pisa (Livorno), Porto Venere, Portoferraio (Elba), Rome (Civitavecchia)
2026 Sails: Aug 13, More...
Norwegian Line Tours, Norwegian Dawn Tours
Norwegian Dawn Tours10 Night - Explore Barcelona Pre Cruisetour
Starting in At Hotel, Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Tangier, Morocco, Cadiz / Seville, Spain, Lisbon, Portugal
2026 Sails: Aug 13, More...
Windstar, Wind Spirit
Wind Spirit7 Night - Masterpieces at Sea : Mediterranean Island Mosaic
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome
2026 Sails: Aug 13, More...
Windstar, Wind Spirit
Wind Spirit14 Night - Star Collector : Captivating Corsica & Sardinia
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome, Bastia, Ajaccio, France, Bonifacio, France, Alghero, Italy, Golfo Aranci, Italy, Rome
2026 Sails: Aug 13, More...
Windstar, Wind Spirit
Wind Spirit21 Night - Star Collector : Mediterranean Crossroads : Spain, France, Italy & Greece
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome, Bastia, Ajaccio, France, Bonifacio, France, Alghero, Italy, Golfo Aranci, Italy, Rome, Sorrento, Messina (Taormina), Gythion, Monemvasia, Athens, Greece
2026 Sails: Aug 13, More...
Ritz-Carlton, Ilma
Ilma7 Night - Barcelona / Monte Carlo
Starting in Barcelona, Ibiza, Balearic Islands, Palma de Mallorca, Mallorca, Balearic Islands, Mahon, Menorca, Balearic Islands, Alghero, Sardinia, Saint-Tropez, Cannes, Monte Carlo
2026 Sails: Aug 14, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox10 Night - Greek Isles & Turkey Cruise
Starting in Barcelona, Spain, Sicily (Messina), Italy, Athens (Piraeus), Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Olympia (Katakolon), Greece, Rome (Civitavecchia), Italy
2026 Sails: Aug 15, More...

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Spain Cruise Departures