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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

EXPLORA I7 Night - A Journey Through Mediterranean Beauty, Artistic Spirit & Eternal Charms
Starting in Barcelona, Ibiza, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome)
2026 Sails: Aug 3, Aug 31, Sep 28, More...
EXPLORA I14 Night - An Extended Journey from Cultural Gems to Riviera Magic & Balmy Beaches
Starting in Barcelona, Ibiza, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome), Porto Santo Stefano (Argentario), Monte Carlo, Saint-Tropez, Tarragona, Palma De Mallorca, Barcelona
2026 Sails: Aug 3, More...
EXPLORA III14 Night - An Extended Journey from Iberian Rhythms to Cultural Crossings
Starting in Barcelona, Palma De Mallorca, Puerto Banus (Marbella), Tangier, Cadiz, Portimao, Lisbon, Porto (Leixoes), La Coruna (a Coruna), Bilbao, Pauillac, Saint-Jean-de-Luz, Southampton
2026 Sails: Aug 3, More...
EXPLORA III7 Night - A Journey of Buzzing Beachside Vibes & Timeless Lyrical Charm
Starting in Barcelona, Palma De Mallorca, Puerto Banus (Marbella), Tangier, Cadiz, Portimao, Lisbon
2026 Sails: Aug 3, More...
Royal Caribbean, Brilliance of the Seas
Brilliance of the Seas7 Night - Italy & France Cruise
Starting in Barcelona, Spain, Provence (Toulon), France, Ajaccio, Corsica, France, Rome (Civitavecchia), Italy, Naples, Italy, Sicily (Messina), Italy, Trieste, Italy
2026 Sails: Aug 3, More...
MSC Cruises, MSC Opera
MSC Opera10 Night - Mediterranean
Starting in Malaga (Granada), Spain, Cadiz (Seville), Spain, Lisbon (Cascais), Portugal, Alicante, Spain, Mahon, Menorca, Spain, Olbia, Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Malaga (Granada), Spain
2026 Sails: Aug 4, More...
Princess Cruises, Sun Princess
Sun Princess21 Night - The Best of the Mediterranean with Total Solar Eclipse
Starting in Barcelona, Spain, Gibraltar, Cartagena ES, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Aug 8, More...
Princess Cruises, Sun Princess
Sun Princess14 Night - Mediterranean with Total Solar Eclipse
Starting in Barcelona, Spain, Gibraltar, Cartagena ES, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Aug 8, More...
Princess Cruises, Sun Princess
Sun Princess7 Night - Mediterranean with Total Solar Eclipse
Starting in Barcelona, Spain, Gibraltar, Cartagena ES, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Aug 8, More...
Atlas Ocean Voyages, World Traveller
World Traveller7 Night - Barcelona to Monte Carlo
Starting in Barcelona, Valencia, Ibiza, Palma De Mallorca, Banyuls-sur-Mer, Sete (Montpellier), Cannes, Monte Carlo
2026 Sails: Aug 9, More...

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Spain Cruise Departures