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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Fantasia
MSC Fantasia5 Night - Mediterranean
Starting in Barcelona, Spain, La Valletta, Malta, Corfu, Greece, Bari, Italy
2026 Sails: Apr 27, More...
MSC Cruises, MSC Fantasia
MSC Fantasia9 Night - Mediterranean
Starting in Barcelona, Spain, La Valletta, Malta, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy, Katakolon (Olympia), Greece, Piraeus (Athens), Greece
2026 Sails: Apr 27, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit13 Night - Cruise from Gran Canaria to Malaga
Starting in Las Palmas / Gran Canaria, Arrecife / Lanzarote, Agadir, Casablanca, Tangier, Cadiz, Gibraltar, Malaga
2026 Sails: Apr 27, More...
Silversea, Silver Ray
Silver Ray11 Night - Barcelona to Barcelona
Starting in Barcelona, Marseille, Ibiza, Palma De Mallorca, Gibraltar, Malaga (Costa del Sol), Cartagena ES, Spain, Valencia, Barcelona
2026 Sails: Apr 27, More...
Silversea, Silver Shadow
Silver Shadow5 Night - Palma De Mallorca to Nice
Starting in Palma De Mallorca, Barcelona, Palamos, Marseille, Nice
2026 Sails: Apr 27, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Palma De Mallorca
Starting in Palma De Mallorca, Valencia, La Spezia, Civitavecchia, Savona, Marseille, Palma De Mallorca
2026 Sails: Apr 28, May 5, More...
PONANT, L'Austral
L'Austral10 Night - Volcanic Islands and Historic Cities of the North Atlantic
Starting in Las Palmas de Gran Canaria, Canary Islands, Santa Cruz de Tenerife, San Sebastian de la Gomera, Canary Islands, Santa Cruz de La Palma, Funchal, Madeira, Portimao, Setubal, Lisbon
2026 Sails: Apr 28, More...
PONANT, Le Bougainville
Le Bougainville7 Night - Iberian Peninsula & Sicily
Starting in Malaga, Cartagena, Valencia, Palma de Mallorca, Balearic Islands, Mahon, Balearic Islands, Trapani, Sicily, Valletta
2026 Sails: Apr 28, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Valencia
Starting in Valencia, La Spezia, Civitavecchia, Savona, Marseille, Palma De Mallorca, Valencia
2026 Sails: Apr 29, May 6, More...
Norwegian Cruise Line, Norwegian Viva
Norwegian Viva9 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Nice / Monaco (Villefranche), France, Livorno / Florence / Pisa, Italy, Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Messina, Italy, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Venice (Ravenna), Italy
2026 Sails: Apr 29, Jun 24, Aug 19, More...

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Spain Cruise Departures