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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Viking Ocean, Viking Neptune
Viking Neptune7 Night - Iconic Western Mediterranean
Starting in Barcelona, Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Sep 26, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Barcelona (Tarragona), Spain
2026 Sails: Sep 27, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema6 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Spain, Cadiz, Spain, Lisbon, Portugal, Gibraltar (UK), Malaga, Spain
2026 Sails: Sep 28, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema11 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Spain, Cadiz, Spain, Lisbon, Portugal, Gibraltar (UK), Malaga, Spain, Cartagena ES, Spain, Marseille, France, Savona, Italy, Barcelona, Spain
2026 Sails: Sep 28, More...
Emerald Cruises, Emerald Sakara
Emerald Sakara10 Night - Pearls of Southern Spain & Portugal
Starting in Barcelona, Spain, Mahon, Menorca, Spain, Palma De Mallorca, Spain, Ibiza, Spain, Cartagena ES, Malaga, Spain, Tangier, Morocco, Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Sep 28, More...
Explora Journeys, EXPLORA I
EXPLORA I14 Night - An Extended Journey of Sunlit Discovery & Timeless Wonder
Starting in Barcelona, Ibiza, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome), La Spezia, Monte Carlo, Saint-Tropez, Mahon (Menorca), Valencia, Barcelona
2026 Sails: Sep 28, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager12 Night - Mediterranean Nights
Starting in Barcelona, Toulon, La Spezia (Cinque Terre), Cruising the Tyrrhenian Sea, Valletta, Cruising the Tyrrhenian Sea, Sorrento / Capri, Rome (Civitavecchia)
2026 Sails: Sep 28, More...
Silversea, Silver Ray
Silver Ray10 Night - Barcelona to Monte Carlo
Starting in Barcelona, Malaga (Costa del Sol), Cartagena ES, Spain, Valencia, Palma De Mallorca, Palamos, Marseille, Saint Tropez, Monte Carlo
2026 Sails: Sep 28, More...
Silversea, Silver Spirit
Silver Spirit10 Night - Barcelona to Civitavecchia
Starting in Barcelona, Palamos, Palma De Mallorca, Sete, Marseille, Monte Carlo, Livorno (Tuscany), Porto Santo Stefano, Civitavecchia (Rome)
2026 Sails: Sep 28, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Palma De Mallorca
Starting in Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Sep 29, More...

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Spain Cruise Departures