Spain Cruise Departures
Cruises that depart from Europe: Spain
Cruises that visit Spain
See all River Cruises that depart from Spain
Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron
14 Night - Taste of Bordeaux with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Pauillac, Cadillac, Bordeaux, Loire Valley / Amboise, Amboise, Paris
2026 Sails: Sep 13, Sep 20, Oct 11, Oct 18, 2027: Mar 7, Apr 11, Apr 18, Apr 25, May 2, May 9, May 23, May 30, Jun 6, Jun 13, Jun 27, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 17, Nov 14, More...14 Night - Taste of Bordeaux with Bilbao, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Pauillac, Cadillac, Bordeaux, Paris
2026 Sails: Sep 13, Sep 20, Oct 4, Oct 18, 2027: Mar 7, Apr 11, Apr 18, Apr 25, May 2, May 9, May 23, May 30, Jun 6, Jun 13, Jun 27, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 17, Nov 14, More...
7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Naples, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona
2026 Sails: Sep 13, Sep 27, Oct 4, More...
7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy, Palermo (Monreale), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 8, More...1 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France
2026 Sails: Sep 13, More...
7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Sep 13, More...
13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Sep 13, More...27 Night - Highlights of Spain - Tour 2C
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 13, More...20 Night - Highlights of Spain - Tour 2B
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 13, More...
7 Night - Western Mediterranean Cruise
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain
2026 Sails: Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, More...
Cruises that depart from Europe: Spain
Cruises that visit Spain
See all River Cruises that depart from Spain
Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron
14 Night - Taste of Bordeaux with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-CruiseStarting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Pauillac, Cadillac, Bordeaux, Loire Valley / Amboise, Amboise, Paris
2026 Sails: Sep 13, Sep 20, Oct 11, Oct 18, 2027: Mar 7, Apr 11, Apr 18, Apr 25, May 2, May 9, May 23, May 30, Jun 6, Jun 13, Jun 27, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 17, Nov 14, More...
14 Night - Taste of Bordeaux with Bilbao, San Sebastian Pre-Cruise and Paris Post CruiseStarting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Pauillac, Cadillac, Bordeaux, Paris
2026 Sails: Sep 13, Sep 20, Oct 4, Oct 18, 2027: Mar 7, Apr 11, Apr 18, Apr 25, May 2, May 9, May 23, May 30, Jun 6, Jun 13, Jun 27, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, Oct 3, Oct 17, Nov 14, More...
7 Night - Western Mediterranean from BarcelonaStarting in Barcelona, Cagliari, Naples, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona
2026 Sails: Sep 13, Sep 27, Oct 4, More...
7 Night - MediterraneanStarting in Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy, Palermo (Monreale), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 8, More...
1 Night - MediterraneanStarting in Barcelona, Spain, Marseille (Provence), France
2026 Sails: Sep 13, More...
7 Night - Europe - Western Mediterranean - BarcelonaStarting in Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Cadiz / Seville, Spain, Portimao, Portugal, Lisbon, Portugal
2026 Sails: Sep 13, More...
13 Night - Highlights of Spain - Tour 2AStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Sep 13, More...
27 Night - Highlights of Spain - Tour 2CStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Naples, Italy (for Capri and Pompeii), Barcelona, Spain
2026 Sails: Sep 13, More...
20 Night - Highlights of Spain - Tour 2BStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Sep 13, More...
7 Night - Western Mediterranean CruiseStarting in Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain
2026 Sails: Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, More...
