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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Costa Cruise Lines, Costa Diadema
Costa Diadema20 Night - Transatlantic from Barcelona
Starting in Barcelona, Malaga, Cadiz, Lisbon, Las Palmas (Gran Canaria), Santa Cruz de Tenerife, Mindelo (Sao Vicente), Maceio, Salvador Bahia, Rio De Janeiro, Santos (Sao Paulo)
2026 Sails: Nov 3, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema17 Night - Transatlantic from Barcelona
Starting in Barcelona, Malaga, Cadiz, Lisbon, Las Palmas (Gran Canaria), Santa Cruz de Tenerife, Mindelo (Sao Vicente), Maceio, Salvador Bahia
2026 Sails: Nov 3, More...
Costa Cruise Lines, Costa Diadema
Costa Diadema16 Night - Transatlantic from Barcelona
Starting in Barcelona, Malaga, Cadiz, Lisbon, Las Palmas (Gran Canaria), Santa Cruz de Tenerife, Mindelo (Sao Vicente), Maceio
2026 Sails: Nov 3, More...
AmaWaterways Tours, AmaVida Tours
AmaVida Tours13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Pinhao, Entre-os-Rios, Porto, Lisbon
2026 Sails: Nov 4, More...
Holland America, Oosterdam
Oosterdam14 Night - Cultural Crossing with Andalusia
Starting in Barcelona, Spain, Cartagena ES, Malaga, Spain, Gibraltar, Kings Wharf, Bermuda, Fort Lauderdale, Florida
2026 Sails: Nov 4, More...
Star Clippers, Star Flyer
Star Flyer24 Night - Westbound Atlantic Ocean Crossing
Starting in Malaga, Spain, Gibraltar, British Overseas Territory, Tangier, Morocco, Cadiz, Spain, Safi, Morocco, Arrecife / Lanzarote / Canary Islands, Spain, Santa Cruz de Tenerife, Las Palmas, Gran Canaria / Canary Islands, Spain, San Sebastian / La Gomera, Spain, Philipsburg, St Maarten
2026 Sails: Nov 4, More...
Star Clippers, Star Flyer
Star Flyer9 Night - Morocco & Canary Islands
Starting in Malaga, Spain, Gibraltar, British Overseas Territory, Tangier, Morocco, Cadiz, Spain, Safi, Morocco, Arrecife / Lanzarote / Canary Islands, Spain, Santa Cruz de Tenerife, Las Palmas, Gran Canaria / Canary Islands, Spain
2026 Sails: Nov 4, More...
Windstar, Star Legend
Star Legend8 Night - Spanish Mystery Cruise
Starting in Barcelona, Mystery Port, Malaga
2026 Sails: Nov 4, More...
Windstar, Star Legend
Star Legend23 Night - Star Collector : Spanish Mystery & Atlantic Crossing
Starting in Barcelona, Mystery Port, Malaga, Tangier, Casablanca, Funchal, Madeira, Bridgetown, Barbados
2026 Sails: Nov 4, More...
MSC Cruises, MSC Magnifica
MSC Magnifica8 Night - Mediterranean
Starting in Tarragona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Nov 5, More...

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Spain Cruise Departures