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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

Silversea, Silver Ray
Silver Ray11 Night - Barcelona to Barcelona
Starting in Barcelona, Ibiza, Palma De Mallorca, Cadiz, Tangier, Malaga (Costa del Sol), Cartagena ES, Spain, Valencia, Barcelona
2026 Sails: Apr 16, More...
Atlas Ocean Voyages, World Navigator
World Navigator14 Night - Tenerife to London
Starting in Santa Cruz de Tenerife, Funchal (Madeira), Lisbon, Porto, Bilbao, Bordeaux, St Malo, Honfleur (Normandy), London (Tower Bridge)
2026 Sails: Apr 17, More...
MSC Cruises, MSC World Europa
MSC World Europa7 Night - Mediterranean
Starting in Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain
2026 Sails: Apr 17, More...
Star Clippers, Star Clipper
Star Clipper8 Night - Malaga to Nice
Starting in Malaga, Spain, Motril, Spain, Ibiza / Balearic Islands, Spain, Palma De Mallorca, Mallorca / Balearic Islands, Spain, Mahon / Menorca / Balearic Islands, Spain, St Tropez, France, Nice, France
2026 Sails: Apr 17, More...
Windstar, Wind Star
Wind Star15 Night - Star Collector : Ancient to Avant-Garde Mediterranean
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome, Ponza, Sorrento, Amalfi, Messina (Taormina), Gythion, Monemvasia, Athens, Greece
2026 Sails: Apr 17, More...
Windstar, Wind Star
Wind Star7 Night - Mediterranean Island Mosaic
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome
2026 Sails: Apr 17, More...
Atlas Ocean Voyages, World Voyager
World Voyager9 Night - Las Palmas to Lisbon
Starting in Las Palmas (Gran Canaria), Arrecife (Lanzarote), Agadir, Safi, Casablanca, Tangier, Morocco, Cadiz, Portimao, Lisbon
2026 Sails: Apr 18, More...
MSC Cruises, MSC Musica
MSC Musica5 Night - Mediterranean
Starting in Barcelona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain
2026 Sails: Apr 18, More...
Scenic Luxury, Scenic Eclipse
Scenic Eclipse7 Night - President's Cruise with Ken Muskat - Mediterranean
Starting in Barcelona, Spain, Mahon, Menorca, Spain, Marseille, France, Monte Carlo, Monaco, Calvi, Corsica, France, Livorno, Italy, Portofino, Italy, Cannes, France / Nice, France
2026 Sails: Apr 18, More...
Sea Cloud, Sea Cloud Spirit
Sea Cloud Spirit10 Night - Canary Islands Roundtrip from Gran Canaria
Starting in Las Palmas / Gran Canaria, San Sebastian / La Gomera, Santa Cruz de La Palma, Puerto De La Estaca / El Hierro, Santa Cruz de Tenerife, Arrecife / Lanzarote, Las Palmas / Gran Canaria
2026 Sails: Apr 18, More...

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Spain Cruise Departures