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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Explora Journeys, EXPLORA I
EXPLORA I14 Night - An Extended Journey Through Sparkling Coasts & Serene Beauty
Starting in Barcelona, Ibiza, Mahon (Menorca), Alghero (Sardinia), Saint-Tropez, Monte Carlo, Barcelona, Cannes, Portofino, Livorno (Florence), Porto Cervo (Sardinia), Ajaccio (Corsica), Civitavecchia (Rome)
2026 Sails: Jun 15, More...
Explora Journeys, EXPLORA I
EXPLORA I7 Night - A Journey of Island Wonders & Serene Riviera Exploration
Starting in Barcelona, Ibiza, Mahon (Menorca), Alghero (Sardinia), Saint-Tropez, Monte Carlo, Barcelona
2026 Sails: Jun 15, More...
Azamara Cruises, Azamara Journey
Azamara Journey10 Night - Spain Intensive Cruise : Valencia, Malaga & Seville
Starting in Barcelona, Valencia, Palma, Majorca, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon
2026 Sails: Jun 16, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda6 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Jun 16, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Alicante
Starting in Alicante, Olbia, Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia
2026 Sails: Jun 17, More...
MSC Cruises, MSC Opera
MSC Opera10 Night - Mediterranean
Starting in Alicante, Spain, Mahon, Spain, Olbia, Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Malaga (Granada), Spain, Cadiz (Seville), Spain, Lisbon (Cascais), Portugal, Alicante, Spain
2026 Sails: Jun 19, Jun 29, Jul 19, Jul 29, Aug 18, Aug 28, Sep 7, Sep 17, Sep 27, More...
AmaVida7 Night - Flavors of Portugal & Spain
Starting in Vega de Terron, Barca dAlva, Pinhao, Regua, Entre-os-Rios, Porto
2026 Sails: Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 26, Oct 10, Nov 7, 2027: Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox10 Night - Greek Isles & Turkey
Starting in Barcelona, Spain, Valletta, Malta, Athens (Piraeus), Greece, Ephesus (Kusadasi), Turkey, Santorini, Greece, Mykonos, Greece, Olympia (Katakolon), Greece, Rome (Civitavecchia), Italy
2026 Sails: Jun 20, Sep 12, More...
Viking Ocean, Viking Star
Viking Star12 Night - Mediterranean Odyssey
Starting in Barcelona, Barcelona (Tarragona), Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sail the Ionian Sea, Corfu (Kerkyra), Dubrovnik, Croatia, Split, Venice (Chioggia)
2026 Sails: Jun 20, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity6 Night - Europe & Mediterranean
Starting in Palma De Mallorca, Alicante, Malaga (Costa del Sol), Tangier, Cadiz, Lisbon
2026 Sails: Jun 21, More...

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Spain Cruise Departures