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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Oceania Cruises, Oceania Allura
Oceania Allura15 Night - Pathway to Sunshine
Starting in Barcelona, Malaga, Agadir, Arrecife (Lanzarote), San Juan, Miami
2026 Sails: Nov 17, More...
Viking Ocean, Viking Neptune
Viking Neptune7 Night - Spain & Portugal Discovery
Starting in Barcelona, Palma De Mallorca, Murcia (Cartagena ES, Spain), Granada (Malaga), Tangier, Seville (Cadiz), Lisbon
2026 Sails: Nov 17, 2027: Feb 12, Apr 9, More...
AmaWaterways Tours, AmaVida Tours
AmaVida Tours13 Night - Flavors of Portugal & Spain (Taste of Christmas) with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Brodenbach, Pinhao, Entre-os-Rios, Porto, Lisbon
2026 Sails: Nov 18, 2027: Nov 17, Dec 1, Dec 15, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa8 Night - Cruise from Las Palmas to Pointe a Pitre
Starting in Las Palmas, Canary Islands, Martinique (Antilles), Guadeloupe (Antilles)
2026 Sails: Nov 18, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa7 Night - Cruise from Las Palmas to Fort de France
Starting in Las Palmas, Canary Islands, Martinique (Antilles)
2026 Sails: Nov 18, More...
MSC Cruises, MSC World Europa
MSC World Europa17 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Arrecife De Lanzarote (Canary Islands), Spain, Santa Cruz de Tenerife, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Kingstown, St Vincent and the Grenadines, Bridgetown, Barbados, Saint George, Grenada, Fort-de-France, Martinique
2026 Sails: Nov 18, More...
MSC Cruises, MSC World Europa
MSC World Europa18 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Arrecife De Lanzarote (Canary Islands), Spain, Santa Cruz de Tenerife, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Kingstown, St Vincent and the Grenadines, Bridgetown, Barbados, Saint George, Grenada, Fort-de-France, Martinique, Pointe-A-Pitre, Guadeloupe
2026 Sails: Nov 18, More...
MSC Cruises, MSC World Europa
MSC World Europa14 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Arrecife De Lanzarote (Canary Islands), Spain, Santa Cruz de Tenerife, Philipsburg, St Maarten, Basseterre, St Kitts and Nevis, Kingstown, St Vincent and the Grenadines, Bridgetown, Barbados
2026 Sails: Nov 18, More...
Silversea, Silver Ray
Silver Ray10 Night - Barcelona to Lisbon
Starting in Barcelona, Valencia, Cartagena ES, Spain, Malaga (Costa del Sol), Casablanca, Tangier, Cadiz, Lisbon
2026 Sails: Nov 18, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox16 Night - Spain to Argentina Transatlantic
Starting in Barcelona, Spain, Tangier, Morocco, Salvador De Bahia, Brazil, Rio De Janeiro, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 19, More...

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Spain Cruise Departures