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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

Departing from
Spain
Cruise Specials

MSC Cruises, MSC Musica
MSC Musica10 Night - Canary Islands and Madeira
Starting in Santa Cruz de Tenerife, Arrecife De Lanzarote (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Casablanca (Marrakesh), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2026 Sails: Apr 12, More...
MSC Cruises, MSC Musica
MSC Musica8 Night - Canary Islands and Madeira
Starting in Santa Cruz de Tenerife, Arrecife De Lanzarote (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Casablanca (Marrakesh), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy
2026 Sails: Apr 12, More...
MSC Cruises, MSC Musica
MSC Musica9 Night - Canary Islands and Madeira
Starting in Santa Cruz de Tenerife, Arrecife De Lanzarote (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Casablanca (Marrakesh), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy
2026 Sails: Apr 12, More...
Viking Ocean, Viking Sea
Viking Sea7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Apr 12, 2027: Mar 19, Apr 30, More...
Viking Ocean, Viking Sea
Viking Sea14 Night - Mediterranean & Italian Sojourn
Starting in Barcelona, Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Apr 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, La Goulette, Palermo, Civitavecchia, Savona, Marseille, Barcelona
2026 Sails: Apr 13, Apr 20, Apr 27, May 4, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda3 Night - Western Mediterranean from Barcelona to Palermo
Starting in Barcelona, La Goulette, Palermo
2026 Sails: Apr 13, More...
MSC Cruises, MSC Musica
MSC Musica7 Night - Canary Islands and Madeira
Starting in Arrecife De Lanzarote (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Casablanca (Marrakesh), Morocco, Barcelona, Spain, Civitavecchia (Rome), Italy
2026 Sails: Apr 13, More...
Windstar, Wind Spirit
Wind Spirit9 Night - Treasures of Southern Spain & Morocco
Starting in Malaga, Tangier, Gibraltar, Almeria, Spain, Cartagena ES, Valencia, Palma De Mallorca, Tarragona, Spain, Barcelona
2026 Sails: Apr 13, More...
Windstar Tours, Wind Spirit Tours
Wind Spirit Tours14 Night - Next Stop Madrid : Spanish Treasures Cruise Tour
Starting in Malaga, Tangier, Gibraltar, Almeria, Spain, Cartagena ES, Valencia, Palma De Mallorca, Tarragona, Spain, Barcelona
2026 Sails: Apr 13, More...

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Spain Cruise Departures