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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Virgin Voyages, Valiant Lady
Valiant Lady7 Night - French Riviera, Italy & Ibiza Overnight
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Civitavecchia (Rome), Italy, Cannes, France, Ibiza, Spain, Barcelona, Spain
2026 Sails: May 31, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel11 Night - Spain, Portugal & Morocco
Starting in Barcelona, Spain, Tangier, Morocco, Madeira (Funchal), Portugal, Lisbon, Portugal, Seville (Cadiz), Spain, Palma De Mallorca, Spain, Barcelona, Spain
2026 Sails: Jun 1, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona
2026 Sails: Jun 1, Jun 22, Jul 6, Sep 28, More...
Azamara Cruises, Azamara Quest
Azamara Quest14 Night - Spain Intensive Cruise : Valencia, Seville & Bilbao
Starting in Barcelona, Valencia, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon, Porto (Leixoes), Bilbao, Pasajes, San Sebastian, Bordeaux
2026 Sails: Jun 2, More...
Azamara Cruises, Azamara Quest
Azamara Quest25 Night - Spain & France Cruise : Seville, Bordeaux & Normandy
Starting in Barcelona, Valencia, Cartagena ES, Malaga, Gibraltar, Seville, Lisbon, Porto (Leixoes), Bilbao, Pasajes, San Sebastian, Bordeaux, Saint Peter Port, Saint-malo, Cherbourg, Rouen (Paris), Honfleur, Dunkirk, Antwerp, Amsterdam (Ijmuiden)
2026 Sails: Jun 2, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Palma De Mallorca
Starting in Palma De Mallorca, Alicante, Olbia, Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca
2026 Sails: Jun 2, Jun 9, Jun 16, More...
Silversea, Silver Shadow
Silver Shadow5 Night - Palma De Mallorca to Nice
Starting in Palma De Mallorca, Barcelona, Palamos, Sete, Marseille, Nice
2026 Sails: Jun 2, Jul 8, Aug 13, More...
Viking Ocean, Viking Sea
Viking Sea7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2026 Sails: Jun 2, 2027: Mar 19, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Alicante
Starting in Alicante, Olbia, Civitavecchia (Rome), Savona, La Seyne (St Tropez), Palma De Mallorca, Alicante
2026 Sails: Jun 3, Jun 10, More...
Emerald Cruises, Emerald Radiance
Emerald Radiance10 Night - Barcelona & Secrets of the Douro
Starting in Barcelona, Barcelona / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto
2026 Sails: Jun 3, More...

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Spain Cruise Departures