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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Silversea, Silver Shadow
Silver Shadow5 Night - Palma De Mallorca to Nice
Starting in Palma De Mallorca, Barcelona, Palamos, Sete, Marseille, Nice
2026 Sails: Aug 13, More...
Windstar, Wind Spirit
Wind Spirit7 Night - Masterpieces at Sea : Mediterranean Island Mosaic
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome
2026 Sails: Aug 13, More...
Windstar, Wind Spirit
Wind Spirit14 Night - Star Collector : Captivating Corsica & Sardinia
Starting in Barcelona, Palma De Mallorca, Mahon, Calvi, Bastia, Portoferraio, Rome, Bastia, Ajaccio, France, Bonifacio, France, Alghero, Italy, Golfo Aranci, Italy, Rome
2026 Sails: Aug 13, More...
Ritz-Carlton, Ilma
Ilma7 Night - Barcelona / Monte Carlo
Starting in Barcelona, Ibiza, Balearic Islands, Palma de Mallorca, Mallorca, Balearic Islands, Mahon, Menorca, Balearic Islands, Alghero, Sardinia, Saint-Tropez, Cannes, Monte Carlo
2026 Sails: Aug 14, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox10 Night - Greek Isles & Turkey Cruise
Starting in Barcelona, Spain, Sicily (Messina), Italy, Athens (Piraeus), Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Olympia (Katakolon), Greece, Rome (Civitavecchia), Italy
2026 Sails: Aug 15, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana7 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Cagliari, Napoli, Civitavecchia (Rome), Genoa (Portofino), Marseille, Barcelona
2026 Sails: Aug 16, Aug 23, Aug 30, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn7 Night - Europe - Western Mediterranean - Barcelona
Starting in Barcelona, Spain, Palma Majorca, Spain, Valencia, Spain, Motril, Spain, Gibraltar, Tangier, Morocco, Cadiz / Seville, Spain, Lisbon, Portugal
2026 Sails: Aug 16, More...
Cunard Line, Queen Victoria
Queen Victoria7 Night - Italy and Spain
Starting in Barcelona, Spain, Ibiza, Spain, Cagliari, Sardinia, Italy, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 17, More...
Cunard Line, Queen Victoria
Queen Victoria14 Night - Italy, Spain and Adriatic
Starting in Barcelona, Spain, Ibiza, Spain, Cagliari, Sardinia, Italy, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy
2026 Sails: Aug 17, More...
Oceania Sirena10 Night - Visions of Byzantium
Starting in Barcelona, Palermo (Sicily), Syracuse IT (Sicily), Argostoli (Cephalonia), Gythion, Paros, Athens (Piraeus), Ephesus (Kusadasi), Bozcaada (Troy), Istanbul
2026 Sails: Aug 17, More...

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Spain Cruise Departures