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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Explora Journeys, EXPLORA I
EXPLORA I19 Night - An Extended Journey from Riviera Icons to Grand Prix Glamour
Starting in Barcelona, Mahon (Menorca), Cannes, Saint-Tropez, Alghero (Sardinia), Civitavecchia (Rome), Monte Carlo, Civitavecchia (Rome), Sorrento, Giardini Naxos, La Valletta, Palma De Mallorca, Barcelona
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I12 Night - An Extended Journey from Mediterranean Radiance to a Legendary Monaco Race Weekend
Starting in Barcelona, Mahon (Menorca), Cannes, Saint-Tropez, Alghero (Sardinia), Civitavecchia (Rome), Monte Carlo
2026 Sails: May 27, More...
Explora Journeys, EXPLORA I
EXPLORA I7 Night - A Journey of Authentic Flavours & Glittering Shorelines
Starting in Barcelona, Mahon (Menorca), Cannes, Saint-Tropez, Alghero (Sardinia), Civitavecchia (Rome), Monte Carlo
2026 Sails: May 27, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Southern Europe from Barcelona to Naples
Starting in Barcelona, Marseille, Savona, Civitavecchia (Rome), Napoli
2026 Sails: May 29, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa12 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia (Rome), Napoli, Palermo, La Goulette, Malta / La Valletta, Catania, Taranto, Argostoli / Cephalonia, Mykonos, Athens (Piraeus)
2026 Sails: May 29, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa9 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia (Rome), Napoli, Palermo, La Goulette, Malta / La Valletta, Catania, Taranto
2026 Sails: May 29, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa8 Night - Eastern Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Civitavecchia (Rome), Napoli, Palermo, La Goulette, Malta / La Valletta, Catania
2026 Sails: May 29, More...
Disney Cruise Line, Disney Dream
Disney Dream9 Night - Mediterranean with Greek Isles Cruise from Barcelona Ending in Civitavecchia
Starting in Barcelona, Messina, Piraeus, Santorini, Mykonos, Chania, Civitavecchia
2026 Sails: May 30, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: May 31, Jun 28, Jul 19, Aug 2, Aug 9, Sep 27, 2027: Mar 14, Mar 21, Mar 28, Apr 4, Jul 4, Jul 11, Jul 18, Aug 1, Aug 8, Aug 15, Sep 26, Nov 21, Nov 28, Dec 5, More...
AmaWaterways Tours, AmaDolce Tours
AmaDolce Tours14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cadillac, Bordeaux, Paris
2026 Sails: May 31, Jun 28, Jul 19, Aug 2, Aug 9, 2027: Mar 14, Mar 21, Mar 28, Apr 4, Jul 4, Jul 11, Jul 18, Aug 1, Aug 8, Aug 15, Sep 26, Nov 21, Nov 28, Dec 5, Dec 12, More...

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Spain Cruise Departures