Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron : Vigo

MSC Cruises, MSC Poesia

Deal link -> Special

14 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Funchal (Madeira Islands), Portugal, Philipsburg, St Maarten, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 9, More...

MSC Cruises, MSC Poesia

32 Night - Msc Grand Voyages
Starting in Barcelona, Spain, Funchal (Madeira Islands), Portugal, Philipsburg, St Maarten, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 9, More...

Costa Cruise Lines, Costa Fascinosa

4 Night - Western Mediterranean from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2026 Sails: Apr 10, Apr 17, Apr 24, May 1, Oct 13, Oct 30, More...

Costa Cruise Lines, Costa Fortuna

8 Night - Cruise from Las Palmas to Savona
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Casablanca, Morocco, Barcelona, Spain, Marseille, France, Savona, Italy
2026 Sails: Apr 10, More...

Costa Cruise Lines, Costa Fortuna

7 Night - Cruise from Las Palmas to Marseille
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Casablanca, Morocco, Barcelona, Spain, Marseille, France
2026 Sails: Apr 10, More...

Costa Cruise Lines, Costa Fortuna

6 Night - Cruise from Las Palmas to Barcelona
Starting in Las Palmas, Canary Islands, Santa Cruz de Tenerife, Funchal (Madeira), Casablanca, Morocco, Barcelona, Spain
2026 Sails: Apr 10, More...

MSC Cruises, MSC Musica

8 Night - Canary Islands and Madeira
Starting in Las Palmas de Gran Canaria (Canary Islands), Spain, Funchal (Madeira Islands), Portugal, Santa Cruz de Tenerife, Arrecife De Lanzarote (Canary Islands), Spain, Puerto Del Rosario / Fuerteventura, Spain, Casablanca (Marrakesh), Morocco, Barcelona, Spain
2026 Sails: Apr 10, More...

Regent Seven Seas, Seven Seas Splendor

9 Night - Plazas & Colonnades
Starting in Barcelona, Mahon, Minorca, Provence (Marseille), Monte Carlo, La Spezia (Cinque Terre), Ajaccio (Corsica), Cruising the Tyrrhenian Sea, Palermo (Sicily), Sorrento / Capri, Rome (Civitavecchia), Barcelona, Mahon, Minorca, Provence (Marseille), Monte Carlo, La Spezia (Cinque Terre), Ajaccio (Corsica), Cruising the Tyrrhenian Sea, Palermo (Sicily), Sorrento / Capri, Rome (Civitavecchia)
2026 Sails: Apr 10, More...

Regent Seven Seas, Seven Seas Voyager

7 Night - Elegant Shores
Starting in Barcelona, Palamos, Sete, Saint-Tropez, Cruising the Liguarian Sea, Tuscany (Livorno), Golfo Aranci (Sardinia), Rome (Civitavecchia), Barcelona, Palamos, Sete, Saint-Tropez, Cruising the Liguarian Sea, Tuscany (Livorno), Golfo Aranci (Sardinia), Rome (Civitavecchia)
2026 Sails: Apr 10, More...

Star Clippers, Star Flyer

9 Night - Malta, Balearics & Spain
Starting in Malaga, Spain, Almeria, Spain, Cartagena ES, Ibiza / Balearic Islands, Spain, Mahon / Menorca / Balearic Islands, Spain, Cagliari / Sardinia, Italy, Gozo, Malta, Valletta, Malta
2026 Sails: Apr 10, 2027: Apr 16, More...

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