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Santo Domingo Cruise Departures

Cruises that depart from Caribbean: Dominican Republic: Santo Domingo

Cruises that visit Santo Domingo

Click on a cruise ship itinerary sailing from Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Costa Cruise Lines, Costa Favolosa
Costa Favolosa7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Dominican Republic, Roseau, Dominica, Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Kitts (Antilles), Tortola, British Virgin Islands, Santo Domingo, Dominican Republic
2027 Sails: Jan 25, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Dominican Republic, Antigua (Antilles), Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Kitts (Antilles), St Maarten (Antilles), Santo Domingo, Dominican Republic
2027 Sails: Feb 1, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa18 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Dominican Republic, St Maarten (Antilles), Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Santa Cruz de Tenerife, Tangier, Morocco, Malaga, Spain, Barcelona, Spain
2027 Sails: Mar 1, More...
Costa Cruise Lines, Costa Favolosa
Costa Favolosa19 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Dominican Republic, St Maarten (Antilles), Martinique (Antilles), Martinique Bay, Guadeloupe (Antilles), St Kitts (Antilles), Antigua (Antilles), Santa Cruz de Tenerife, Tangier, Morocco, Malaga, Spain, Barcelona, Spain, Marseille, France
2027 Sails: Mar 1, More...

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Santo Domingo Cruise Departures