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Dominican Republic Cruise Departures

Cruises that depart from Caribbean: Dominican Republic

Cruises that visit Dominican Republic

Click on a cruise ship itinerary sailing from Dominican Republic (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Dominican Republic), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Casa de Campo : La Romana : Punta Cana : Santo Domingo


Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa7 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo
2026 Sails: Feb 23, Mar 2, More...
Norwegian Cruise Line, Norwegian Sky
Norwegian Sky7 Night - Caribbean
Starting in Punta Cana (La Romana), Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Kralendijk, Netherland Antilles, St Lucia, Saint Lucia, Basseterre, Saint Kitts / Nevis, Tortola, British Virgin Islands, Punta Cana (La Romana), Dominican Republic
2026 Sails: Feb 23, Mar 2, Mar 16, Mar 23, Mar 30, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Caribbean from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre
2026 Sails: Mar 2, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Caribbean from Casa De Campo / La Romana
Starting in La Romana, Catalina Island, Cabo Rojo, Grand Turk, Amber Cove, Samana (Do), La Romana
2026 Sails: Mar 8, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica21 Night - Transatlantic from Casa De Campo / La Romana
Starting in Casa de Campo, Dominican Republic, Catalina Island, Dominican Republic, Catalina Bay, Cabo Rojo, Grand Turk, Turks and Caicos, Archipelago, Turks and Caicos, Amber Cove, Dominican Republic, Samana, Dominican Republic, Casa de Campo, Dominican Republic, St Maarten (Antilles), Santa Cruz de Tenerife, Cadiz, Spain, Barcelona, Spain, Marseille, France
2026 Sails: Mar 8, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa18 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre, Castries, St Lucia, Bridgetown, Barbados, Santa Cruz de Tenerife, Tangier, Barcelona, Marseille
2026 Sails: Mar 9, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa17 Night - Transatlantic from Santo Domingo
Starting in Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre, Castries, St Lucia, Bridgetown, Barbados, Santa Cruz de Tenerife, Tangier, Barcelona
2026 Sails: Mar 9, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica14 Night - Transatlantic from Casa De Campo / La Romana
Starting in Casa de Campo, Dominican Republic, St Maarten (Antilles), Santa Cruz de Tenerife, Cadiz, Spain, Barcelona, Spain, Marseille, France
2026 Sails: Mar 15, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica13 Night - Transatlantic from Casa De Campo / La Romana
Starting in La Romana, St Maarten (Philipsburg), Santa Cruz de Tenerife, Cadice, Barcelona
2026 Sails: Mar 15, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica15 Night - Caribbean from La Romana to Savona
Starting in La Romana, St Maarten (Philipsburg), Santa Cruz de Tenerife, Cadice, Barcelona, Marseille, Savona
2026 Sails: Mar 15, More...

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Dominican Republic Cruise Departures