Santo Domingo Cruises
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
6 Night - Western Caribbean from Fort De France
Starting in Fort-de-France, Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France
2025 Sails: Dec 18, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France, St Lucia Castries, Pointe-a-Pitre
2025 Sails: Dec 19, More...5 Night - Western Caribbean from Pointe a Pitre
Starting in Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France
2025 Sails: Dec 19, More...7 Night - Western Caribbean from Fort De France
Starting in Fort-de-France, St Lucia Castries, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Fort-de-France
2025 Sails: Dec 24, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Fort-de-France, St Johns AG, Antigua, Pointe-a-Pitre
2025 Sails: Dec 26, More...8 Night - Western Caribbean from Fort De France
Starting in Fort-de-France, St Johns AG, Antigua, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2025 Sails: Dec 31, More...7 Night - Western Caribbean from Pointe a Pitre
Starting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre
2026 Sails: Jan 2, Jan 9, More...6 Night - Cruise from Pointe a Pitre to Fort de France
Starting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2026 Sails: Jan 2, More...
55 Night - Star Collector : Grand Caribbean Adventure
Starting in Philipsburg, St Maarten, Falmouth Harbour, Road Bay, Sopers Hole, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, Gustavia, Philipsburg, St Maarten, Basseterre, Gustavia, St Johns, Les Saintes, Roseau, Mayreau, Bridgetown, Anse Mitan, Castries, Pigeon Island, Bequia, Mayreau, St Georges, Bridgetown, Bequia, Mayreau, Soufriere, Kralendijk, Willemstad AN, Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon, Bocas del Toro, Isla San Andres, Roatan, Belize City, Costa Maya, Mexico, Cozumel, Mexico, Grand Cayman, Cayman Brac, Ocho Rios, Jamaica, Santo Domingo, La Romana, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, Philipsburg, St Maarten
2026 Sails: Jan 4, More...7 Night - Western Caribbean from Fort De France
Starting in Fort-de-France, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2026 Sails: Jan 8, More...
Cruises that visit Caribbean: Dominican Republic: Santo Domingo
Cruises that depart from Santo Domingo
Click on a cruise ship itinerary that visits Santo Domingo (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Santo Domingo), please visit: Cruise Search or try our Virtual Cruise Advisor™.
6 Night - Western Caribbean from Fort De FranceStarting in Fort-de-France, Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France
2025 Sails: Dec 18, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France, St Lucia Castries, Pointe-a-Pitre
2025 Sails: Dec 19, More...
5 Night - Western Caribbean from Pointe a PitreStarting in Pointe-a-Pitre, St Maarten (Philipsburg), Basseterre, Santo Domingo, Fort-de-France
2025 Sails: Dec 19, More...
7 Night - Western Caribbean from Fort De FranceStarting in Fort-de-France, St Lucia Castries, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Fort-de-France
2025 Sails: Dec 24, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Fort-de-France, St Johns AG, Antigua, Pointe-a-Pitre
2025 Sails: Dec 26, More...
8 Night - Western Caribbean from Fort De FranceStarting in Fort-de-France, St Johns AG, Antigua, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2025 Sails: Dec 31, More...
7 Night - Western Caribbean from Pointe a PitreStarting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France, Pointe-a-Pitre
2026 Sails: Jan 2, Jan 9, More...
6 Night - Cruise from Pointe a Pitre to Fort de FranceStarting in Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2026 Sails: Jan 2, More...
55 Night - Star Collector : Grand Caribbean AdventureStarting in Philipsburg, St Maarten, Falmouth Harbour, Road Bay, Sopers Hole, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, Gustavia, Philipsburg, St Maarten, Basseterre, Gustavia, St Johns, Les Saintes, Roseau, Mayreau, Bridgetown, Anse Mitan, Castries, Pigeon Island, Bequia, Mayreau, St Georges, Bridgetown, Bequia, Mayreau, Soufriere, Kralendijk, Willemstad AN, Oranjestad, Cartagena CO, San Blas, Panama, Bocas del Toro, Colon, Bocas del Toro, Isla San Andres, Roatan, Belize City, Costa Maya, Mexico, Cozumel, Mexico, Grand Cayman, Cayman Brac, Ocho Rios, Jamaica, Santo Domingo, La Romana, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, Philipsburg, St Maarten
2026 Sails: Jan 4, More...
7 Night - Western Caribbean from Fort De FranceStarting in Fort-de-France, Pointe-a-Pitre, Basseterre, Tortola (Road Harbour), Santo Domingo, Catalina Island, Fort-de-France
2026 Sails: Jan 8, More...
