Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
7 Night - Greek Isles Cruise
Starting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, More...
11 Night - Greece, Turkey & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Santorini, Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 4, Jun 15, Aug 17, Oct 19, 2027: May 24, Jul 5, Aug 16, Sep 27, More...
13 Night - Lake Como & Adriatic Romance Cruise Tour
Starting in Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice, Venice, Italy, Cernobbio
2026 Sails: May 4, More...9 Night - Classic Italy & Dalmatian Coast
Starting in Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: May 4, More...
9 Night - Italian Riviera & France
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: May 5, Jun 2, More...
7 Night - Rome (Civitavecchia) / Monte Carlo
Starting in Rome (Civitavecchia), Portoferraio, Elba, Bastia, Corsica, Livorno, Portofino, Cannes, Monte Carlo
2026 Sails: May 6, More...
7 Night - Ancient Sands
Starting in Rome (Civitavecchia), Naples / Pompeii, Valletta, Cruising the Mediterranean Sea, Katakolon, Santorini, Mykonos, Athens (Piraeus)
2026 Sails: May 8, More...
7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: May 9, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)
Starting in Rome (Civitavecchia), Sorrento, Pylos, Chania (Souda), Crete, Santorini, Milos, Athens (Piraeus)
2026 Sails: May 11, More...
7 Night - Adriatic & Ionian Artistry
Starting in Rome (Civitavecchia), Salerno, Taormina (Sicily), Argostoli (Cephalonia), Tirana (Durres), Hvar, Zadar, Venice (Fusina)
2026 Sails: May 12, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Greek Isles CruiseStarting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, More...
11 Night - Greece, Turkey & Italy CruiseStarting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Santorini, Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 4, Jun 15, Aug 17, Oct 19, 2027: May 24, Jul 5, Aug 16, Sep 27, More...
13 Night - Lake Como & Adriatic Romance Cruise TourStarting in Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice, Venice, Italy, Cernobbio
2026 Sails: May 4, More...
9 Night - Classic Italy & Dalmatian CoastStarting in Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: May 4, More...
9 Night - Italian Riviera & FranceStarting in Rome (Civitavecchia), Italy, Naples, Italy, Florence / Pisa (La Spezia), Italy, Portofino, Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: May 5, Jun 2, More...
7 Night - Rome (Civitavecchia) / Monte CarloStarting in Rome (Civitavecchia), Portoferraio, Elba, Bastia, Corsica, Livorno, Portofino, Cannes, Monte Carlo
2026 Sails: May 6, More...
Deal link -> Special
7 Night - Ancient SandsStarting in Rome (Civitavecchia), Naples / Pompeii, Valletta, Cruising the Mediterranean Sea, Katakolon, Santorini, Mykonos, Athens (Piraeus)
2026 Sails: May 8, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: May 9, More...
7 Night - Rome (Civitavecchia) / Athens (Piraeus)Starting in Rome (Civitavecchia), Sorrento, Pylos, Chania (Souda), Crete, Santorini, Milos, Athens (Piraeus)
2026 Sails: May 11, More...
7 Night - Adriatic & Ionian ArtistryStarting in Rome (Civitavecchia), Salerno, Taormina (Sicily), Argostoli (Cephalonia), Tirana (Durres), Hvar, Zadar, Venice (Fusina)
2026 Sails: May 12, More...
