Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
8 Night - A Journey to Italian Hidden Gems & the Heartbeat of Catalan Culture
Starting in Rome (Civitavecchia), Sorrento, Palermo (Sicily), Tunis / La Goulette, Ibiza, Mahon (Menorca), Barcelona, Monte Carlo
2026 Sails: May 13, More...
7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: May 13, More...
10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Olympia (Katakolon), Greece, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Montenegro, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 15, Aug 7, Sep 18, More...
11 Night - Best of Italy & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: May 18, More...
7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: May 19, More...
7 Night - Rome (Civitavecchia) / Nice
Starting in Rome (Civitavecchia), Portoferraio, Elba, Livorno, Monte Carlo, Ajaccio, Corsica, Calvi, Corsica, Nice
2026 Sails: May 20, More...
10 Night - Sicilian Splendors
Starting in Rome, Syracuse, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome
2026 Sails: May 21, More...13 Night - Historic Harbors of Italy & Beyond
Starting in Rome, Syracuse, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome, Porto Venere, Bonifacio, France, Rome
2026 Sails: May 21, More...
10 Night - Italy & France Spotlight
Starting in Rome (Civitavecchia), Amalfi / Positano, Palermo (Sicily), Olbia / Porto Cervo (Sardinia), Bastia (Corsica), Piombino (Tuscany), Florence / Pisa / Tuscany (Livorno), Villefranche, Saint-Tropez, Toulon, Barcelona
2026 Sails: May 22, More...
13 Night - Spotlight On Faberge
Starting in Rome (Civitavecchia), Tuscany (Livorno), Monte Carlo, Barcelona, Cruising the Mediterranean Sea, Cruising the Atlantic Ocean, La Coruna, Cruising the English Channel, Paris (Honfleur), London (Southampton)
2026 Sails: May 24, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - A Journey to Italian Hidden Gems & the Heartbeat of Catalan CultureStarting in Rome (Civitavecchia), Sorrento, Palermo (Sicily), Tunis / La Goulette, Ibiza, Mahon (Menorca), Barcelona, Monte Carlo
2026 Sails: May 13, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: May 13, More...
10 Night - Italy, Greece & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Olympia (Katakolon), Greece, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Montenegro, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: May 15, Aug 7, Sep 18, More...
11 Night - Best of Italy & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: May 18, More...
7 Night - Iconic Western MediterraneanStarting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: May 19, More...
7 Night - Rome (Civitavecchia) / NiceStarting in Rome (Civitavecchia), Portoferraio, Elba, Livorno, Monte Carlo, Ajaccio, Corsica, Calvi, Corsica, Nice
2026 Sails: May 20, More...
10 Night - Sicilian SplendorsStarting in Rome, Syracuse, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome
2026 Sails: May 21, More...
13 Night - Historic Harbors of Italy & BeyondStarting in Rome, Syracuse, Italy, Valletta, Gozo, Porto Empedocle, Trapani, Lipari, Sorrento, Amalfi, Rome, Porto Venere, Bonifacio, France, Rome
2026 Sails: May 21, More...
Deal link -> Special
10 Night - Italy & France SpotlightStarting in Rome (Civitavecchia), Amalfi / Positano, Palermo (Sicily), Olbia / Porto Cervo (Sardinia), Bastia (Corsica), Piombino (Tuscany), Florence / Pisa / Tuscany (Livorno), Villefranche, Saint-Tropez, Toulon, Barcelona
2026 Sails: May 22, More...
Deal link -> Special
13 Night - Spotlight On FabergeStarting in Rome (Civitavecchia), Tuscany (Livorno), Monte Carlo, Barcelona, Cruising the Mediterranean Sea, Cruising the Atlantic Ocean, La Coruna, Cruising the English Channel, Paris (Honfleur), London (Southampton)
2026 Sails: May 24, More...
