Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
8 Night - Winter in Italy and the Adriatic
Starting in Rome, Naples, Catania, Crotone, Italy, Corfu (Kerkyra), Delphi, Corinth Canal, Athens, Greece
2026 Sails: Mar 31, More...
14 Night - Ancient Mediterranean Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 8, More...7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Apr 8, More...
11 Night - France Intensive Cruise : Mysteries & Lore
Starting in Rome (Civitavecchia), Bonifacio, Cannes, Monte Carlo, Sete, Sanary-sur-mer, Provence (Marseille), St Tropez, Menton, Nice
2026 Sails: Apr 17, More...
9 Night - Pesto, Paella & Paradise
Starting in Rome (Civitavecchia), Portoferraio (Elba Island), La Spezia (Cinque Terre), Villefranche, Cruising the Balearic Sea, Alicante, Valencia, Ibiza, Barcelona (Tarragona)
2026 Sails: Apr 17, More...
13 Night - Venetian Vistas
Starting in Rome (Civitavecchia), Amalfi / Positano, Trapani (Sicily), La Goulette, Valletta, Cruising the Mediterranean Sea, Argostoli (Cephalonia), Brindisi, Kotor, Dubrovnik, Croatia, Split, Cruising the Adriatic Sea, Koper, Venice (Fusina)
2026 Sails: Apr 19, More...
21 Night - Adriatic & Mediterranean Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 19, More...14 Night - Italy, the Adriatic & Greece
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Apr 19, More...7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Apr 19, More...
9 Night - Greek Isles Cruise
Starting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Apr 24, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Winter in Italy and the AdriaticStarting in Rome, Naples, Catania, Crotone, Italy, Corfu (Kerkyra), Delphi, Corinth Canal, Athens, Greece
2026 Sails: Mar 31, More...
14 Night - Ancient Mediterranean AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 8, More...
7 Night - Journey to AntiquitiesStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Apr 8, More...
11 Night - France Intensive Cruise : Mysteries & LoreStarting in Rome (Civitavecchia), Bonifacio, Cannes, Monte Carlo, Sete, Sanary-sur-mer, Provence (Marseille), St Tropez, Menton, Nice
2026 Sails: Apr 17, More...
Deal link -> Special
9 Night - Pesto, Paella & ParadiseStarting in Rome (Civitavecchia), Portoferraio (Elba Island), La Spezia (Cinque Terre), Villefranche, Cruising the Balearic Sea, Alicante, Valencia, Ibiza, Barcelona (Tarragona)
2026 Sails: Apr 17, More...
13 Night - Venetian VistasStarting in Rome (Civitavecchia), Amalfi / Positano, Trapani (Sicily), La Goulette, Valletta, Cruising the Mediterranean Sea, Argostoli (Cephalonia), Brindisi, Kotor, Dubrovnik, Croatia, Split, Cruising the Adriatic Sea, Koper, Venice (Fusina)
2026 Sails: Apr 19, More...
21 Night - Adriatic & Mediterranean SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 19, More...
14 Night - Italy, the Adriatic & GreeceStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Apr 19, More...
7 Night - Italian SojournStarting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Apr 19, More...
9 Night - Greek Isles CruiseStarting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Apr 24, More...
