Panama City Cruise Departures
Cruises that depart from Central America: Panama: Panama City
Cruises that visit Panama City
10 Night - Panama, Ecuadaor & Peru Cruise : Panama City, Manta & Lima (Callao)
Starting in Panama City (Fuerte Amador), Manta, Callao (Lima), Pisco, Coquimbo, Valparaiso
2028 Sails: Jan 14, More...
10 Night - Classic Canal & Tropics
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Willemstad AN, Oranjestad, Montego Bay, George Town, Miami
2028 Sails: Jan 16, More...
7 Night - Coastal Adventures : Panama & Costa Rica
Starting in Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 24, 2029: Jan 24, More...11 Night - Panama Canal Transit, Colombia & the Grenadines
Starting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 29, 2029: Mar 1, More...
26 Night - Azure to Iberia
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami, Cruising the Atlantic Ocean, Royal Naval Dockyard, Cruising the Atlantic Ocean, Ponta Delgada (Azores), Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon
2028 Sails: Mar 14, More...12 Night - Bon Bini Aruba
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami
2028 Sails: Mar 14, More...10 Night - Spanish Lullaby
Starting in Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 15, More...
13 Night - Ancient Kingdoms & Natural Treasures : Panama to Chile
Starting in Panama City, Panama, Darien National Park, Playa del Muerto, Panama, Utria National Natural Park, Ensenada de Utria, Colombia, Manta, Ecuador, Salaverry, Peru, Paracas, Peru, Pinguino de Humboldt National Reserve, Chile, Valparaiso, Chile
2028 Sails: Oct 24, More...18 Night - Discover Panama, Costa Rica and Barbados
Starting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados, Bridgetown / Speightstown, Barbados, Kingstown / Bequia Island, Saint Vincent, The Grenadines, Bequia Island / Mayreau Island, Saint Vincent, The Grenadines, Mayreau Island / Union Island, Saint Vincent and the Grenadines, Union Island, Saint Vincent, The Grenadines, Union Island / Tobago Cays, Saint Vincent, The Grenadines, Bridgetown, Barbados
2029 Sails: Mar 1, More...
Cruises that depart from Central America: Panama: Panama City
Cruises that visit Panama City
Click on a cruise ship itinerary sailing from Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Panama, Ecuadaor & Peru Cruise : Panama City, Manta & Lima (Callao)Starting in Panama City (Fuerte Amador), Manta, Callao (Lima), Pisco, Coquimbo, Valparaiso
2028 Sails: Jan 14, More...
10 Night - Classic Canal & TropicsStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Willemstad AN, Oranjestad, Montego Bay, George Town, Miami
2028 Sails: Jan 16, More...
7 Night - Coastal Adventures : Panama & Costa RicaStarting in Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 24, 2029: Jan 24, More...
11 Night - Panama Canal Transit, Colombia & the GrenadinesStarting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 29, 2029: Mar 1, More...
26 Night - Azure to IberiaStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami, Cruising the Atlantic Ocean, Royal Naval Dockyard, Cruising the Atlantic Ocean, Ponta Delgada (Azores), Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon
2028 Sails: Mar 14, More...
12 Night - Bon Bini ArubaStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami
2028 Sails: Mar 14, More...
10 Night - Spanish LullabyStarting in Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 15, More...
13 Night - Ancient Kingdoms & Natural Treasures : Panama to ChileStarting in Panama City, Panama, Darien National Park, Playa del Muerto, Panama, Utria National Natural Park, Ensenada de Utria, Colombia, Manta, Ecuador, Salaverry, Peru, Paracas, Peru, Pinguino de Humboldt National Reserve, Chile, Valparaiso, Chile
2028 Sails: Oct 24, More...
18 Night - Discover Panama, Costa Rica and BarbadosStarting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados, Bridgetown / Speightstown, Barbados, Kingstown / Bequia Island, Saint Vincent, The Grenadines, Bequia Island / Mayreau Island, Saint Vincent, The Grenadines, Mayreau Island / Union Island, Saint Vincent and the Grenadines, Union Island, Saint Vincent, The Grenadines, Union Island / Tobago Cays, Saint Vincent, The Grenadines, Bridgetown, Barbados
2029 Sails: Mar 1, More...
