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Panama City Cruise Departures

Cruises that depart from Central America: Panama: Panama City

Cruises that visit Panama City

Click on a cruise ship itinerary sailing from Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Regent Seven Seas Cruises, Seven Seas Prestige
Seven Seas Prestige Cruises26 Night - Azure to Iberia
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami, Cruising the Atlantic Ocean, Royal Naval Dockyard, Cruising the Atlantic Ocean, Ponta Delgada (Azores), Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon
2028 Sails: Mar 14, More...
Regent Seven Seas Cruises, Seven Seas Prestige
Seven Seas Prestige Cruises12 Night - Bon Bini Aruba
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami
2028 Sails: Mar 14, More...
Oceania Cruises, Oceania Marina
Oceania Marina Cruise Ship10 Night - Spanish Lullaby
Starting in Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 15, More...

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Panama City Cruise Departures