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Panama City Cruise Departures

Cruises that depart from Central America: Panama: Panama City

Cruises that visit Panama City

Click on a cruise ship itinerary sailing from Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Emerald Cruises, Emerald Azzurra
Emerald Azzurra18 Night - Discover Panama, Costa Rica and Barbados
Starting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados, Bridgetown / Speightstown, Barbados, Kingstown / Bequia Island, Saint Vincent, The Grenadines, Bequia Island / Mayreau Island, Saint Vincent, The Grenadines, Mayreau Island / Union Island, Saint Vincent and the Grenadines, Union Island, Saint Vincent, The Grenadines, Union Island / Tobago Cays, Saint Vincent, The Grenadines, Bridgetown, Barbados
2029 Sails: Mar 1, More...

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Panama City Cruise Departures