Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
Panama Cruise Departures

Cruises that depart from Central America: Panama

Cruises that visit Panama

Click on a cruise ship itinerary sailing from Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Balboa : Colon : Fuerte Amador : Panama City

Departing from
Panama
Cruise Specials

Crystal, Crystal Serenity
Crystal Serenity Cruise Ship11 Night - The Americas & Caribbean
Starting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...
Azamara, Azamara Quest
Azamara Quest Cruise Ship10 Night - Panama, Ecuadaor & Peru Cruise : Panama City, Manta & Lima (Callao)
Starting in Panama City (Fuerte Amador), Manta, Callao (Lima), Pisco, Coquimbo, Valparaiso
2028 Sails: Jan 14, More...
Oceania Cruises, Oceania Marina
Oceania Marina Cruise Ship10 Night - Classic Canal & Tropics
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Willemstad AN, Oranjestad, Montego Bay, George Town, Miami
2028 Sails: Jan 16, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra Cruises7 Night - Coastal Adventures : Panama & Costa Rica
Starting in Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 24, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra Cruises11 Night - Panama Canal Transit, Colombia & the Grenadines
Starting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 29, More...
Regent Seven Seas Cruises, Seven Seas Prestige
Seven Seas Prestige Cruises26 Night - Azure to Iberia
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami, Cruising the Atlantic Ocean, Royal Naval Dockyard, Cruising the Atlantic Ocean, Ponta Delgada (Azores), Cruising the Atlantic Ocean, Funchal (Madeira), Cruising the Atlantic Ocean, Cadiz, Lisbon
2028 Sails: Mar 14, More...
Regent Seven Seas Cruises, Seven Seas Prestige
Seven Seas Prestige Cruises12 Night - Bon Bini Aruba
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Cruising the Caribbean Sea, Oranjestad, Willemstad AN, Cruising the Caribbean Sea, St Georges, Roseau, Charlotte Amalie, Cruising the Atlantic Ocean, Cruising the Bahamian Waters, Miami
2028 Sails: Mar 14, More...
Oceania Cruises, Oceania Marina
Oceania Marina Cruise Ship10 Night - Spanish Lullaby
Starting in Panama City, Panama Canal Daylight Transit, Puerto Limon, Roatan, Santo Tomas, Costa Maya, Mexico, Cozumel, Mexico, Miami
2028 Sails: Mar 15, More...

<= Back

Panama Cruise Departures