New Orleans Cruise Departures
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Costa Maya, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Cozumel, Mexico, New Orleans, La
2026 Sails: Mar 22, More...
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 25, More...
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Oct 18, Oct 24, Oct 30, Nov 5, Nov 11, Nov 17, Nov 23, Nov 29, 2027: Mar 27, Apr 2, Apr 8, More...8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 5, More...7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 12, Apr 26, More...9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 17, May 1, More...
7 Night - Western Caribbean
Starting in New Orleans, La, Mahogany Bay, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Apr 19, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 28, 2027: Mar 26, Apr 9, Apr 23, May 7, Oct 29, Nov 12, Dec 21, 2028: Apr 8, Apr 22, May 6, May 20, Oct 28, Nov 11, Nov 25, More...9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 24, More...
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Costa Maya, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Cozumel, Mexico, New Orleans, La
2026 Sails: Mar 22, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 25, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Oct 18, Oct 24, Oct 30, Nov 5, Nov 11, Nov 17, Nov 23, Nov 29, 2027: Mar 27, Apr 2, Apr 8, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 5, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 12, Apr 26, More...
9 Night - Historic New Orleans Pre CruisetourStarting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 17, May 1, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Mahogany Bay, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Apr 19, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 28, 2027: Mar 26, Apr 9, Apr 23, May 7, Oct 29, Nov 12, Dec 21, 2028: Apr 8, Apr 22, May 6, May 20, Oct 28, Nov 11, Nov 25, More...
9 Night - Historic New Orleans Pre CruisetourStarting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 24, More...
