Louisiana Cruise Departures
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Related areas: New Orleans
11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Sep 22, Oct 10, Oct 27, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, More...
6 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2026 Sails: Nov 1, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, More...7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Jamaica, New Orleans, Louisiana
2026 Sails: Nov 7, Nov 14, Nov 21, Nov 28, Dec 12, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 17, More...
7 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Belize, Isla Tropicale, Roatan, New Orleans, La
2026 Sails: Nov 8, 2027: Dec 26, More...
7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...6 Night - Western Caribbean
Starting in New Orleans, La, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 15, Dec 13, 2027: Nov 14, More...
9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 20, Nov 27, Dec 11, Dec 18, Dec 25, More...8 Night - Bahamas
Starting in New Orleans, La, Celebration Key, the Bahamas, Relaxaway, Half Moon Cay, Nassau, Bahamas, New Orleans, La
2026 Sails: Nov 21, More...
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: New Orleans
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Sep 22, Oct 10, Oct 27, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, Nov 10, Nov 24, More...
6 Night - Western Caribbean CruiseStarting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2026 Sails: Nov 1, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, Jun 27, More...
7 Night - Western Caribbean CruiseStarting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Jamaica, New Orleans, Louisiana
2026 Sails: Nov 7, Nov 14, Nov 21, Nov 28, Dec 12, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 17, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Belize, Isla Tropicale, Roatan, New Orleans, La
2026 Sails: Nov 8, 2027: Dec 26, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
6 Night - Western CaribbeanStarting in New Orleans, La, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 15, Dec 13, 2027: Nov 14, More...
9 Night - Historic New Orleans Pre CruisetourStarting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 20, Nov 27, Dec 11, Dec 18, Dec 25, More...
8 Night - BahamasStarting in New Orleans, La, Celebration Key, the Bahamas, Relaxaway, Half Moon Cay, Nassau, Bahamas, New Orleans, La
2026 Sails: Nov 21, More...
